C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000165117 Cdk6-202 ENSMUSG00000040274 10090 + 5:3343893-3523218 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000165117
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000165117 2.713±1.70 1.521±0.60 0.091±0.00 1.382±1.06 3.417±0.80 1.807±0.00 1.472±0.38 1.611±0.45 5.887±0.78 0.091±0.04 4.389±1.36 0.415±0.22 0.384±0.22

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000307 IEA cyclin-dependent protein kinase holoenzyme complex
GO:0001726 IEA ruffle
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0003323 IEA type B pancreatic cell development
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007049 IEA cell cycle
GO:0007219 IDA Notch signaling pathway
GO:0009615 IEA response to virus
GO:0010468 IEA regulation of gene expression
GO:0010628 IDA positive regulation of gene expression
GO:0016301 IDA kinase activity
GO:0030097 IMP hemopoiesis
GO:0030332 IEA cyclin binding
GO:0033077 IMP T cell differentiation in thymus
GO:0042063 IEA gliogenesis
GO:0043697 IEA cell dedifferentiation
GO:0045638 IEA negative regulation of myeloid cell differentiation
GO:0045646 IEA regulation of erythrocyte differentiation
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045786 IEA negative regulation of cell cycle
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0051301 IEA cell division
GO:0060218 IMP hematopoietic stem cell differentiation
GO:2000773 IEA negative regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000102888 cdk6-201 protein_coding Danio_rerio 0 442
ENSDART00000151269 cdk6-001 protein_coding Danio_rerio 0 442
ENST00000265734 CDK6-001 protein_coding Homo_sapiens 0 1624
ENST00000424848 CDK6-002 protein_coding Homo_sapiens 0 1273
ENST00000467166 CDK6-003 retained_intron Homo_sapiens 0 643

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