C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040390 Map3k10 10090 - 7:27656375-27674598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036453 Map3k10-001 27656375-27674594 protein_coding
  ENSMUST00000108341 Map3k10-201 27656664-27674598 protein_coding
  ENSMUST00000133551 Map3k10-004 27664180-27674357 retained_intron
  ENSMUST00000138243 Map3k10-002 27668148-27674581 retained_intron
  ENSMUST00000152032 Map3k10-003 27664158-27665107 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036453ENSMUST00000108341ENSMUST00000133551ENSMUST00000138243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036453 5.292±1.34 8.846±1.18 4.878±0.39 35.164±6.88 5.388±2.58 4.383±0.32 4.070±0.76 4.398±0.72 0.855±0.30 4.121±0.95 12.226±1.71 9.327±1.79 2.167±1.63 11.281±3.60
ENSMUST00000108341 N/A N/A N/A 44.045±0.00 0.195±0.00 N/A N/A N/A N/A N/A 3.720±0.53 8.913±0.00 1.701±1.34 5.362±0.00
ENSMUST00000133551 N/A N/A N/A N/A 1.251±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000138243 8.088±0.94 14.723±4.44 4.948±0.00 N/A 4.987±2.76 9.562±1.07 1.661±0.10 5.281±1.23 4.580±1.94 7.769±1.21 3.745±0.00 9.817±3.07 2.847±0.85 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0003714 IDA transcription corepressor activity
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0007224 IEA smoothened signaling pathway
GO:0008219 IEA cell death
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043425 IEA bHLH transcription factor binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046330 IEA positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055672 map3k10 mitogen-activated protein kinase kinase kinase 10 protein_coding Danio_rerio
ENSG00000130758 MAP3K10 mitogen-activated protein kinase kinase kinase 10 protein_coding Homo_sapiens

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