C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000108341 Map3k10-201 ENSMUSG00000040390 10090 - 7:27656664-27674598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastMuscleOvaryPlacentaTestisENSMUST00000108341
Transcript ID Brain Breast Muscle Ovary Placenta Testis
ENSMUST00000108341 44.045±0.00 0.195±0.00 3.720±0.53 8.913±0.00 1.701±1.34 5.362±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0003714 IDA transcription corepressor activity
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0007224 IEA smoothened signaling pathway
GO:0008219 IEA cell death
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043425 IEA bHLH transcription factor binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046330 IEA positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000088309 map3k10-201 protein_coding Danio_rerio 0.00000003 66
ENSDART00000136432 map3k10-001 protein_coding Danio_rerio 0.00000003 66
ENST00000253055 MAP3K10-001 protein_coding Homo_sapiens 0 3334
ENST00000309100 MAP3K11-001 protein_coding Homo_sapiens 0 442
ENST00000524848 MAP3K11-005 nonsense_mediated_decay Homo_sapiens 0 233
ENST00000524856 MAP3K11-002 retained_intron Homo_sapiens 0 287
ENST00000526293 MAP3K11-012 protein_coding Homo_sapiens 0 235
ENST00000529839 MAP3K11-013 protein_coding Homo_sapiens 0 231
ENST00000530153 MAP3K11-004 protein_coding Homo_sapiens 0 287
ENST00000530949 MAP3K11-011 retained_intron Homo_sapiens 0 231
ENST00000534110 MAP3K11-010 retained_intron Homo_sapiens 8.00001e-42 174
ENST00000593502 MAP3K10-004 nonsense_mediated_decay Homo_sapiens 0 268
ENST00000593906 MAP3K10-005 processed_transcript Homo_sapiens 0 318
ENST00000594951 MAP3K10-003 nonsense_mediated_decay Homo_sapiens 0 717
ENST00000597986 MAP3K10-002 nonsense_mediated_decay Homo_sapiens 0 1227
ENST00000601702 MAP3K10-006 retained_intron Homo_sapiens 0 363

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