C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy/beclin 1 regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040506 Ambra1 10090 + 2:91730134-91918849 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045699 Ambra1-004 91766445-91918849 protein_coding
  ENSMUST00000045705 Ambra1-002 91730225-91918849 protein_coding
  ENSMUST00000099712 Ambra1-001 91730134-91918849 protein_coding
  ENSMUST00000111316 Ambra1-003 91730184-91918848 protein_coding
  ENSMUST00000111317 Ambra1-201 91730138-91918848 protein_coding
  ENSMUST00000124132 Ambra1-005 91730182-91810969 processed_transcript
  ENSMUST00000133490 Ambra1-006 91773232-91824519 processed_transcript
  ENSMUST00000142224 Ambra1-008 91811668-91825352 processed_transcript
  ENSMUST00000156496 Ambra1-007 91730182-91810969 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045699ENSMUST00000045705ENSMUST00000099712ENSMUST00000111316ENSMUST00000111317
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045699 1.360±0.00 N/A 1.162±0.00 5.173±0.00 3.093±0.00 N/A 1.081±0.27 2.020±0.69 0.912±0.23 N/A 1.195±0.60 6.678±0.81 2.455±1.04 1.973±0.16
ENSMUST00000045705 3.771±0.94 N/A 2.120±0.28 6.062±3.59 2.968±1.20 N/A 1.867±0.55 2.469±0.45 0.843±0.24 2.618±1.30 1.536±0.51 3.898±1.38 3.097±1.41 3.843±1.24
ENSMUST00000099712 3.587±0.77 4.681±0.83 2.270±0.14 1.521±0.28 4.536±1.50 5.583±1.04 1.330±0.26 3.615±1.00 2.146±0.74 4.990±0.46 1.388±0.53 4.622±1.61 2.627±0.68 4.357±1.95
ENSMUST00000111316 N/A 7.813±1.90 N/A N/A 3.641±1.30 3.894±0.71 N/A 1.094±0.00 0.953±0.28 2.297±0.13 N/A 4.591±2.22 N/A N/A
ENSMUST00000111317 1.915±0.35 2.985±0.75 N/A 4.783±1.16 1.510±0.36 2.271±0.78 0.867±0.17 1.658±0.18 1.006±0.01 1.352±0.04 1.880±0.31 3.177±1.02 1.059±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 ISA cytoplasm
GO:0005930 IDA axoneme
GO:0006914 IMP autophagy
GO:0008285 IMP negative regulation of cell proliferation
GO:0021915 IMP neural tube development
GO:0030154 IEA cell differentiation
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045335 IDA phagocytic vesicle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008322 AMBRA1 (1 of 2) autophagy/beclin-1 regulator 1 protein_coding Danio_rerio
ENSDARG00000039878 ambra1b autophagy/beclin-1 regulator 1b protein_coding Danio_rerio
ENSG00000110497 AMBRA1 autophagy/beclin-1 regulator 1 protein_coding Homo_sapiens

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