C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy/beclin-1 regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110497 AMBRA1 9606 - 11:46396414-46594125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314845 AMBRA1-006 46396414-46591364 protein_coding
  ENST00000458649 AMBRA1-005 46396415-46591423 protein_coding
  ENST00000524783 AMBRA1-014 46546071-46547420 processed_transcript
  ENST00000526545 AMBRA1-011 46397384-46417995 protein_coding
  ENST00000526606 AMBRA1-008 46548309-46594125 protein_coding
  ENST00000528950 AMBRA1-007 46397450-46594045 protein_coding
  ENST00000529553 AMBRA1-012 46434849-46493893 retained_intron
  ENST00000529558 AMBRA1-010 46504479-46530607 processed_transcript
  ENST00000529963 AMBRA1-013 46490998-46495511 processed_transcript
  ENST00000531542 AMBRA1-009 46545701-46593998 processed_transcript
  ENST00000533727 AMBRA1-002 46396414-46593948 protein_coding
  ENST00000534300 AMBRA1-001 46396414-46594021 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314845ENST00000458649ENST00000526545ENST00000528950ENST00000533727ENST00000534300
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314845 N/A N/A N/A N/A N/A N/A N/A 0.165±0.00 N/A N/A N/A N/A N/A N/A
ENST00000458649 N/A N/A 0.427±0.00 2.211±0.00 2.011±0.00 1.039±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000526545 N/A N/A N/A N/A N/A N/A N/A 1.432±0.00 N/A N/A N/A N/A N/A N/A
ENST00000528950 N/A N/A N/A 0.872±0.00 N/A N/A N/A N/A 0.726±0.00 N/A N/A 0.561±0.00 N/A N/A
ENST00000533727 1.989±0.00 2.295±0.00 0.459±0.00 2.928±1.33 1.390±0.00 2.612±0.00 1.860±0.00 2.152±0.00 N/A 1.932±0.00 2.713±0.00 3.129±0.80 2.094±0.90 2.466±0.00
ENST00000534300 N/A N/A N/A 1.903±0.00 N/A 0.600±0.00 0.537±0.00 N/A N/A 2.262±0.00 N/A 1.008±0.00 1.182±0.21 2.599±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002LK CIL_0002LK_0002 CGP 11:46385098-46594125

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005930 ISS axoneme
GO:0006914 IEA autophagy
GO:0008285 IEA negative regulation of cell proliferation
GO:0021915 IEA neural tube development
GO:0030154 IEA cell differentiation
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045335 IEA phagocytic vesicle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008322 AMBRA1 (1 of 2) autophagy/beclin-1 regulator 1 protein_coding Danio_rerio
ENSDARG00000039878 ambra1b autophagy/beclin-1 regulator 1b protein_coding Danio_rerio
ENSMUSG00000040506 Ambra1 autophagy/beclin 1 regulator 1 protein_coding Mus_musculus

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