C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAP-kinase activating death domain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040687 Madd 10090 - 2:91137360-91183837 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066420 Madd-013 91161393-91183047 protein_coding
  ENSMUST00000066473 Madd-201 91137361-91183818 protein_coding
  ENSMUST00000075269 Madd-005 91137360-91183818 protein_coding
  ENSMUST00000077941 Madd-001 91137360-91183818 protein_coding
  ENSMUST00000099723 Madd-010 91137360-91182889 protein_coding
  ENSMUST00000099725 Madd-202 91137360-91179321 protein_coding
  ENSMUST00000111369 Madd-008 91137360-91179326 protein_coding
  ENSMUST00000111370 Madd-006 91137360-91182848 protein_coding
  ENSMUST00000111371 Madd-004 91137360-91183818 protein_coding
  ENSMUST00000111372 Madd-003 91137360-91183818 protein_coding
  ENSMUST00000111373 Madd-009 91137360-91179315 protein_coding
  ENSMUST00000111375 Madd-007 91137360-91179317 protein_coding
  ENSMUST00000111376 Madd-011 91137360-91182888 protein_coding
  ENSMUST00000111381 Madd-002 91137360-91183818 protein_coding
  ENSMUST00000125227 Madd-025 91137361-91183818 processed_transcript
  ENSMUST00000125321 Madd-023 91137361-91183818 processed_transcript
  ENSMUST00000130395 Madd-014 91161046-91183026 retained_intron
  ENSMUST00000130591 Madd-019 91143042-91154951 retained_intron
  ENSMUST00000132791 Madd-020 91152147-91154795 retained_intron
  ENSMUST00000135715 Madd-015 91177637-91183837 retained_intron
  ENSMUST00000135910 Madd-026 91143271-91152491 retained_intron
  ENSMUST00000140600 Madd-017 91167816-91175729 protein_coding
  ENSMUST00000146097 Madd-018 91155558-91160357 retained_intron
  ENSMUST00000150461 Madd-022 91137361-91183818 processed_transcript
  ENSMUST00000150517 Madd-016 91178449-91183039 processed_transcript
  ENSMUST00000153688 Madd-024 91137361-91183818 processed_transcript
  ENSMUST00000154028 Madd-012 91137361-91183818 processed_transcript
  ENSMUST00000156368 Madd-021 91138350-91139256 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066420ENSMUST00000066473ENSMUST00000077941ENSMUST00000099723ENSMUST00000099725ENSMUST00000111369ENSMUST00000111370ENSMUST00000111372ENSMUST00000111373ENSMUST00000111375ENSMUST00000111376ENSMUST00000111381ENSMUST00000125321ENSMUST00000130395ENSMUST00000154028
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066420 1.754±0.00 3.336±0.60 N/A N/A 3.384±0.44 3.296±0.57 0.734±0.00 1.155±0.00 1.048±0.00 N/A N/A 2.412±0.73 N/A 1.269±0.48
ENSMUST00000066473 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.685±0.00 N/A N/A
ENSMUST00000077941 N/A 0.790±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000099723 0.860±0.00 N/A N/A 4.772±0.73 N/A N/A N/A 0.903±0.00 0.608±0.00 N/A 0.284±0.00 1.110±0.00 N/A N/A
ENSMUST00000099725 N/A N/A N/A 8.426±4.64 3.697±1.40 2.445±0.97 0.710±0.26 1.034±0.38 1.489±0.00 3.865±1.16 N/A 1.495±0.47 N/A N/A
ENSMUST00000111369 N/A N/A 0.910±0.00 N/A N/A N/A 0.544±0.00 0.654±0.00 N/A N/A 0.347±0.00 1.629±0.52 0.781±0.00 N/A
ENSMUST00000111370 0.879±0.02 N/A 1.318±0.00 19.353±6.04 1.970±0.34 2.386±0.23 N/A 1.396±0.27 1.157±0.52 2.864±0.00 0.276±0.05 1.503±0.46 0.587±0.20 0.774±0.07
ENSMUST00000111372 1.269±0.25 N/A 2.087±0.30 N/A 3.253±0.84 N/A 1.048±0.00 1.930±0.57 3.124±2.48 3.789±0.82 0.287±0.08 1.843±0.55 0.715±0.25 1.232±0.41
ENSMUST00000111373 1.116±0.50 N/A N/A N/A 1.850±0.10 N/A 0.542±0.11 1.154±0.15 1.290±0.40 2.085±0.00 0.269±0.00 1.379±0.45 0.496±0.17 0.770±0.09
ENSMUST00000111375 0.821±0.07 N/A 1.480±0.00 N/A 3.133±0.00 N/A N/A N/A 0.600±0.15 N/A 0.251±0.07 1.044±0.02 0.868±0.44 N/A
ENSMUST00000111376 0.764±0.00 N/A N/A N/A N/A N/A N/A 0.795±0.00 N/A N/A 0.359±0.04 1.614±0.00 N/A 0.487±0.00
ENSMUST00000111381 1.579±0.00 1.025±0.20 N/A N/A 2.606±0.00 1.696±0.45 0.658±0.11 N/A N/A 3.208±0.76 N/A N/A N/A N/A
ENSMUST00000125321 N/A N/A N/A N/A 1.406±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000130395 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.615±0.00 N/A N/A
ENSMUST00000154028 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.186±0.00 N/A 0.327±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00017Z CIL_00017Z_0002 CGP 2:91137360-91202834

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0016021 IEA integral component of membrane
GO:0017112 IEA Rab guanyl-nucleotide exchange factor activity
GO:0032483 IEA regulation of Rab protein signal transduction
GO:0032851 IEA positive regulation of Rab GTPase activity
GO:0042981 IEA regulation of apoptotic process
GO:0051726 IEA regulation of cell cycle
GO:0097194 IEA execution phase of apoptosis
GO:1902041 IEA regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001234 IMP negative regulation of apoptotic signaling pathway
GO:2001236 IEA regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003495 madd MAP-kinase activating death domain protein_coding Danio_rerio
ENSG00000110514 MADD MAP-kinase activating death domain protein_coding Homo_sapiens

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