C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041189 Chrnb1 10090 - 11:69784036-69795943 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045971 Chrnb1-001 69784036-69795943 protein_coding
  ENSMUST00000129381 Chrnb1-004 69792779-69793820 retained_intron
  ENSMUST00000147791 Chrnb1-002 69793520-69795905 processed_transcript
  ENSMUST00000154816 Chrnb1-003 69792704-69794270 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045971ENSMUST00000147791
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045971 3.115±0.60 0.527±0.17 6.961±3.07 3.321±1.13 1.629±0.83 1.800±0.44 2.421±0.54 0.262±0.14 10.672±1.40 13.397±1.25 2.446±1.46 3.773±1.86 0.106±0.04
ENSMUST00000147791 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.501±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001941 IEA postsynaptic membrane organization
GO:0003009 IEA skeletal muscle contraction
GO:0004889 IGI acetylcholine-activated cation-selective channel activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005892 IDA acetylcholine-gated channel complex
GO:0006812 IGI cation transport
GO:0006936 IEA muscle contraction
GO:0007165 IEA signal transduction
GO:0007271 IEA synaptic transmission, cholinergic
GO:0007274 IEA neuromuscular synaptic transmission
GO:0015267 IEA channel activity
GO:0015276 IEA ligand-gated ion channel activity
GO:0015464 IEA acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0035095 IEA behavioral response to nicotine
GO:0042166 IMP acetylcholine binding
GO:0042391 IGI regulation of membrane potential
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0048747 IEA muscle fiber development
GO:0050877 IEA neurological system process
GO:0055085 IEA transmembrane transport
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022532 chrnb1l cholinergic receptor, nicotinic, beta 1 (muscle) like protein_coding Danio_rerio
ENSDARG00000069660 chrnb1 cholinergic receptor, nicotinic, beta 1 (muscle) protein_coding Danio_rerio
ENSG00000170175 CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) protein_coding Homo_sapiens

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