C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PHD finger protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041229 Phf8 10090 + X:151520672-151633859 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046950 Phf8-001 151521187-151633859 protein_coding
  ENSMUST00000046962 Phf8-004 151521181-151625833 protein_coding
  ENSMUST00000112662 Phf8-201 151520672-151625833 protein_coding
  ENSMUST00000112666 Phf8-002 151520672-151570807 protein_coding
  ENSMUST00000112668 Phf8-005 151521187-151589220 protein_coding
  ENSMUST00000112670 Phf8-003 151521169-151600386 protein_coding
  ENSMUST00000138318 Phf8-006 151629817-151633859 retained_intron
  ENSMUST00000141715 Phf8-008 151554260-151556483 retained_intron
  ENSMUST00000148622 Phf8-007 151522360-151550991 protein_coding
  ENSMUST00000151941 Phf8-009 151566037-151575836 protein_coding
  ENSMUST00000168501 Phf8-202 151520672-151633857 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046950ENSMUST00000046962ENSMUST00000112670ENSMUST00000138318ENSMUST00000151941ENSMUST00000168501
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046950 3.504±0.92 N/A 2.680±0.01 3.085±0.64 2.146±0.70 2.124±0.24 0.915±0.20 1.254±0.26 1.022±0.33 1.780±0.38 0.996±0.16 2.448±1.93 9.004±8.33 3.738±1.41
ENSMUST00000046962 N/A N/A N/A 3.428±0.00 N/A 1.116±0.00 N/A N/A N/A N/A N/A 4.315±0.00 5.375±2.00 8.728±0.00
ENSMUST00000112670 N/A 2.554±0.50 N/A N/A 2.896±0.12 0.714±0.00 N/A N/A N/A 1.222±0.00 N/A 1.699±0.41 N/A N/A
ENSMUST00000138318 5.113±1.04 4.116±0.87 2.642±0.18 4.757±0.33 5.573±0.87 2.288±0.66 1.277±0.21 2.572±0.43 1.850±0.49 3.329±0.29 0.457±0.12 3.762±1.22 3.933±3.40 2.390±0.29
ENSMUST00000151941 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 27.062±0.00 43.825±19.00 N/A
ENSMUST00000168501 N/A N/A N/A 0.903±0.00 N/A N/A 0.307±0.05 N/A 0.369±0.15 N/A 0.255±0.10 1.019±0.32 0.490±0.00 0.761±0.08

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 ISS G1/S transition of mitotic cell cycle
GO:0003682 ISS chromatin binding
GO:0005506 ISS iron ion binding
GO:0005634 ISS nucleus
GO:0005730 ISS nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0007420 ISS brain development
GO:0008270 IEA:ISS zinc ion binding
GO:0016706 ISS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032452 ISS histone demethylase activity
GO:0032454 ISS histone demethylase activity (H3-K9 specific)
GO:0033169 ISS histone H3-K9 demethylation
GO:0035064 ISS methylated histone binding
GO:0035574 ISS histone H4-K20 demethylation
GO:0035575 ISS histone demethylase activity (H4-K20 specific)
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045943 ISS positive regulation of transcription from RNA polymerase I promoter
GO:0051864 ISS histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0061188 ISS negative regulation of chromatin silencing at rDNA
GO:0070544 ISS histone H3-K36 demethylation
GO:0071557 ISS histone H3-K27 demethylation
GO:0071558 ISS histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006584 phf8 PHD finger protein 8 protein_coding Danio_rerio
ENSG00000172943 PHF8 PHD finger protein 8 protein_coding Homo_sapiens

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