C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium inwardly-rectifying channel, subfamily J, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041695 Kcnj2 10090 + 11:111066164-111076821 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042970 Kcnj2-001 111066164-111076821 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042970 1.374±0.30 1.254±0.37 0.938±0.05 0.981±0.08 3.194±2.19 0.432±0.17 7.596±1.11 0.677±0.10 0.268±0.23 3.853±0.23 10.246±2.18 1.317±0.53 0.241±0.20 0.090±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L0 CIL_0001L0_0003 CGP 11:110968033-111076821
CIL_00072G CIL_00072G_0002 CGP 11:111066164-112787760

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005242 ISS inward rectifier potassium channel activity
GO:0005515 IPI protein binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005791 IEA rough endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006813 ISS potassium ion transport
GO:0008076 IEA voltage-gated potassium channel complex
GO:0010107 IEA potassium ion import
GO:0014704 IEA intercalated disc
GO:0014861 IEA regulation of skeletal muscle contraction via regulation of action potential
GO:0015693 IDA magnesium ion transport
GO:0030315 IEA T-tubule
GO:0030425 IEA dendrite
GO:0031224 ISS intrinsic component of membrane
GO:0042802 IPI identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043197 IEA dendritic spine
GO:0051289 ISS protein homotetramerization
GO:0055119 IEA relaxation of cardiac muscle
GO:0060306 IEA regulation of membrane repolarization
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071805 IEA potassium ion transmembrane transport
GO:0086001 IMP cardiac muscle cell action potential
GO:0086002 IEA cardiac muscle cell action potential involved in contraction
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:0086008 IEA voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086011 IEA membrane repolarization during action potential
GO:0086013 IEA membrane repolarization during cardiac muscle cell action potential
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:0090076 IEA relaxation of skeletal muscle
GO:1901381 IEA positive regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019418 kcnj2a potassium inwardly-rectifying channel, subfamily J, member 2a protein_coding Danio_rerio
ENSDARG00000038373 kcnj2b potassium inwardly-rectifying channel, subfamily J, member 2b protein_coding Danio_rerio
ENSG00000123700 KCNJ2 potassium inwardly-rectifying channel, subfamily J, member 2 protein_coding Homo_sapiens

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