C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 17F
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041872 Il17f 10090 - 1:20777146-20790617 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039046 Il17f-001 20777146-20784270 protein_coding
  ENSMUST00000189301 Il17f-003 20777783-20790617 protein_coding
  ENSMUST00000190692 Il17f-004 20787479-20790585 processed_transcript
  ENSMUST00000191111 Il17f-002 20777679-20779554 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039046ENSMUST00000189301ENSMUST00000190692ENSMUST00000191111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039046 N/A N/A N/A 0.056±0.00 N/A 0.135±0.01 N/A 0.123±0.07 0.068±0.03 N/A 0.043±0.00 0.180±0.09 N/A 0.088±0.00
ENSMUST00000189301 0.589±0.54 0.094±0.00 0.320±0.00 0.667±0.00 5.596±1.32 0.233±0.12 0.084±0.00 0.216±0.01 0.158±0.11 0.168±0.08 0.114±0.06 0.726±0.23 0.177±0.07 0.154±0.06
ENSMUST00000190692 1.052±0.00 0.195±0.00 N/A 0.335±0.00 10.644±11.90 N/A 0.069±0.00 0.118±0.00 0.070±0.00 N/A N/A 0.583±0.31 N/A 0.174±0.07
ENSMUST00000191111 N/A N/A N/A 0.095±0.00 N/A N/A N/A 0.462±0.29 N/A N/A 0.058±0.00 0.531±0.00 N/A 0.134±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081C CIL_00081C_0002 VISTA 1:20619958-21222635
CIL_0005N3 CIL_0005N3_0002 CGP 1:20730905-20790617
CIL_0005N2 CIL_0005N2_0002 CGP 1:20777146-20820312

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005126 IPI cytokine receptor binding
GO:0005615 IDA extracellular space
GO:0006029 IEA proteoglycan metabolic process
GO:0006954 IEA inflammatory response
GO:0016525 IEA negative regulation of angiogenesis
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0019955 IEA cytokine binding
GO:0042089 IEA cytokine biosynthetic process
GO:0042109 IEA lymphotoxin A biosynthetic process
GO:0042803 IEA protein homodimerization activity
GO:0045076 IEA regulation of interleukin-2 biosynthetic process
GO:0045408 IEA regulation of interleukin-6 biosynthetic process
GO:0045414 IEA regulation of interleukin-8 biosynthetic process
GO:0045423 IEA regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051216 IEA cartilage development
GO:1900017 IDA positive regulation of cytokine production involved in inflammatory response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041976 il17a/f3 interleukin 17a/f3 protein_coding Danio_rerio
ENSDARG00000043933 il17a/f1 interleukin 17a/f1 protein_coding Danio_rerio
ENSG00000112116 IL17F interleukin 17F protein_coding Homo_sapiens

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