C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rap guanine nucleotide exchange factor (GEF) 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041992 Rapgef5 10090 + 12:117516479-117756978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000109691 Rapgef5-201 117516479-117756978 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000109691
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109691 1.389±0.00 1.774±0.97 2.268±0.24 4.424±0.00 1.340±0.39 0.808±0.15 1.713±0.53 0.578±0.29 18.501±0.00 0.391±0.00 0.991±0.88 2.078±0.11 3.183±1.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008OS CIL_0008OS_0002 VISTA 12:117505673-118106846

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005634 ISS nucleus
GO:0007264 IEA small GTPase mediated signal transduction
GO:0017034 ISS Rap guanyl-nucleotide exchange factor activity
GO:0030742 ISS GTP-dependent protein binding
GO:0032854 ISS positive regulation of Rap GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074307 rapgef5b Rap guanine nucleotide exchange factor (GEF) 5b protein_coding Danio_rerio
ENSDARG00000075271 rapgef5a Rap guanine nucleotide exchange factor (GEF) 5a protein_coding Danio_rerio
ENSG00000136237 RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 protein_coding Homo_sapiens

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