C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acetyl-Coenzyme A carboxylase beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042010 Acacb 10090 + 5:114146535-114250761 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031583 Acacb-201 114165518-114250755 protein_coding
  ENSMUST00000102582 Acacb-001 114146535-114250761 protein_coding
  ENSMUST00000142489 Acacb-004 114248333-114248958 processed_transcript
  ENSMUST00000143276 Acacb-003 114199779-114250759 processed_transcript
  ENSMUST00000146841 Acacb-002 114175906-114190338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031583ENSMUST00000102582ENSMUST00000143276
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031583 11.895±2.29 21.258±3.68 N/A 0.144±0.00 24.804±10.14 2.261±0.37 17.592±2.81 4.619±1.09 3.445±3.34 3.306±0.84 23.693±2.85 2.407±0.72 0.305±0.05 0.447±0.16
ENSMUST00000102582 4.258±0.34 N/A 0.620±0.13 0.070±0.00 6.122±0.82 N/A 9.994±0.44 2.697±0.40 1.758±0.88 1.857±0.00 17.472±1.78 1.155±0.62 0.360±0.07 0.173±0.06
ENSMUST00000143276 9.005±0.58 N/A 0.461±0.04 0.129±0.00 13.163±0.76 0.814±0.00 13.015±2.71 4.031±1.51 3.518±2.17 2.503±0.39 N/A 1.650±0.23 1.552±0.81 0.401±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041E CIL_00041E_0002 CGP 5:114130386-114250761
CIL_0001VV CIL_0001VV_0002 CGP 5:114146535-114273807

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003989 IDA acetyl-CoA carboxylase activity
GO:0004075 IEA biotin carboxylase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0006084 IEA acetyl-CoA metabolic process
GO:0006633 IMP fatty acid biosynthetic process
GO:0009374 IEA biotin binding
GO:0010884 IMP positive regulation of lipid storage
GO:0014070 IEA response to organic cyclic compound
GO:0042493 IEA response to drug
GO:0046322 IMP negative regulation of fatty acid oxidation
GO:0046872 IEA metal ion binding
GO:0051289 IEA protein homotetramerization
GO:0060421 IMP positive regulation of heart growth
GO:2001295 IMP malonyl-CoA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061994 acacb acetyl-CoA carboxylase beta protein_coding Danio_rerio
ENSG00000076555 ACACB acetyl-CoA carboxylase beta protein_coding Homo_sapiens

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