C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042284 Itga1 10090 - 13:114958079-115101964 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061673 Itga1-201 114958079-115101964 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061673
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061673 6.903±1.92 3.632±0.78 0.635±0.17 4.182±0.70 4.758±1.84 3.140±0.39 9.426±1.49 1.772±0.59 21.247±2.70 0.568±0.00 4.104±1.52 3.102±1.68 2.070±1.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004PM CIL_0004PM_0002 CGP 13:114958079-115101964

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001669 IEA acrosomal vesicle
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005518 IEA collagen binding
GO:0005886 TAS plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 IMP cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008285 ISS negative regulation of cell proliferation
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0019903 IEA protein phosphatase binding
GO:0030593 IMP neutrophil chemotaxis
GO:0032516 ISS positive regulation of phosphoprotein phosphatase activity
GO:0034665 IEA integrin alpha1-beta1 complex
GO:0042059 IMP negative regulation of epidermal growth factor receptor signaling pathway
GO:0042311 IEA vasodilation
GO:0043005 IEA neuron projection
GO:0043204 IEA perikaryon
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045121 IEA membrane raft
GO:0045123 IMP cellular extravasation
GO:0045178 IDA basal part of cell
GO:0046872 IEA metal ion binding
GO:0048812 IEA neuron projection morphogenesis
GO:0060326 IEA cell chemotaxis
GO:0070062 IEA extracellular vesicular exosome
GO:0098639 IEA collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074316 itga1 integrin, alpha 1 protein_coding Danio_rerio
ENSG00000213949 ITGA1 integrin, alpha 1 protein_coding Homo_sapiens

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