C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042807 Hecw2 10090 - 1:53806876-54195168 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000087659 Hecw2-201 53806882-54195034 protein_coding
  ENSMUST00000097741 Hecw2-202 53930813-54195034 protein_coding
  ENSMUST00000120904 Hecw2-001 53806876-54194048 protein_coding
  ENSMUST00000146850 Hecw2-002 53941496-54195168 retained_intron
  ENSMUST00000150677 Hecw2-004 53832692-53841171 processed_transcript
  ENSMUST00000152870 Hecw2-003 53839017-53866512 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087659ENSMUST00000097741ENSMUST00000120904ENSMUST00000146850
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087659 1.115±0.28 0.685±0.27 0.210±0.08 0.891±0.15 0.396±0.00 N/A 0.694±0.34 0.715±0.20 0.149±0.08 1.475±0.95 0.231±0.06 0.426±0.08 0.458±0.49 0.290±0.00
ENSMUST00000097741 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.680±0.02
ENSMUST00000120904 0.313±0.00 1.082±0.20 0.074±0.00 0.490±0.37 0.579±0.20 0.195±0.06 N/A 1.025±0.00 0.152±0.05 3.025±0.65 N/A 1.004±0.32 N/A N/A
ENSMUST00000146850 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.098±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KD CIL_0002KD_0002 CGP 1:53755506-54195168
CIL_0002KC CIL_0002KC_0002 CGP 1:53806876-54368727

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IBA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062447 hecw2a HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a protein_coding Danio_rerio
ENSDARG00000063253 HECW2 (2 of 2) HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 protein_coding Danio_rerio
ENSG00000138411 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 protein_coding Homo_sapiens

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