C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkB, alkylation repair homolog 2 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044339 Alkbh2 10090 - 5:114123926-114128218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053657 Alkbh2-001 114123926-114128176 protein_coding
  ENSMUST00000112279 Alkbh2-002 114123935-114128218 protein_coding
  ENSMUST00000149418 Alkbh2-003 114127606-114128181 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053657ENSMUST00000112279ENSMUST00000149418
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053657 N/A N/A N/A N/A N/A N/A N/A 0.579±0.00 0.766±0.00 N/A 0.259±0.00 1.269±0.23 N/A 0.262±0.00
ENSMUST00000112279 5.401±0.20 4.842±1.48 3.832±0.20 4.411±1.28 3.744±1.14 4.176±1.42 0.869±0.49 3.772±0.73 3.684±0.71 3.188±0.30 0.637±0.22 7.248±2.18 10.140±3.06 0.899±0.30
ENSMUST00000149418 N/A 2.270±0.19 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.247±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VU CIL_0001VU_0002 CGP 5:114100333-114128218
CIL_0001VT CIL_0001VT_0002 CGP 5:114123926-114139323

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0006307 ISS DNA dealkylation involved in DNA repair
GO:0008198 ISS ferrous iron binding
GO:0016706 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0035511 ISS oxidative DNA demethylation
GO:0043734 ISS DNA-N1-methyladenine dioxygenase activity
GO:0051747 ISS cytosine C-5 DNA demethylase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059856 alkbh2 alkB, alkylation repair homolog 2 (E. coli) protein_coding Danio_rerio
ENSG00000189046 ALKBH2 alkB, alkylation repair homolog 2 (E. coli) protein_coding Homo_sapiens

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