C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkB, alkylation repair homolog 2 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000189046 ALKBH2 9606 - 12:109088188-109093631 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343075 ALKBH2-001 109088189-109093472 protein_coding
  ENST00000429722 ALKBH2-007 109088197-109093459 protein_coding
  ENST00000440112 ALKBH2-003 109088222-109092789 protein_coding
  ENST00000536242 ALKBH2-005 109090037-109093469 protein_coding
  ENST00000536358 ALKBH2-008 109090125-109093472 protein_coding
  ENST00000536720 ALKBH2-004 109092255-109093631 retained_intron
  ENST00000543444 ALKBH2-009 109089620-109092752 protein_coding
  ENST00000619381 ALKBH2-201 109088188-109093488 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343075ENST00000429722ENST00000440112ENST00000536242ENST00000536358ENST00000536720ENST00000619381
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343075 4.785±0.00 5.367±0.00 1.391±0.00 4.136±1.49 2.187±0.81 1.863±1.52 0.928±0.43 2.339±1.59 5.841±0.00 3.980±0.00 4.102±1.53 4.413±0.81 2.017±0.35 5.281±0.00
ENST00000429722 2.046±0.00 1.806±0.00 N/A 2.810±0.01 1.163±0.64 2.112±1.13 1.332±0.00 1.817±0.00 3.887±2.32 1.835±0.00 1.433±0.63 4.474±1.70 1.851±0.59 3.977±0.27
ENST00000440112 4.710±0.00 3.826±0.00 N/A 4.094±0.00 4.871±0.00 1.991±0.00 0.861±0.00 4.141±0.00 N/A N/A N/A 5.227±0.08 2.442±0.76 3.316±0.03
ENST00000536242 N/A N/A N/A 3.460±0.00 N/A 2.574±0.00 0.754±0.00 2.181±0.00 N/A N/A N/A N/A 1.056±0.00 N/A
ENST00000536358 N/A 1.915±0.00 N/A 1.061±0.00 N/A 0.327±0.00 N/A 0.974±0.00 N/A N/A N/A 6.392±0.00 0.970±0.00 4.813±0.00
ENST00000536720 N/A N/A 2.927±0.00 N/A 0.594±0.00 N/A N/A 2.265±0.00 N/A N/A N/A N/A N/A N/A
ENST00000619381 N/A N/A N/A N/A N/A 0.864±0.00 0.633±0.00 N/A 0.592±0.00 N/A 1.019±0.52 4.876±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VU CIL_0001VU_0001 CGP 12:109023089-109093631
CIL_0001VT CIL_0001VT_0001 CGP 12:109088188-109110992

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0006307 IDA DNA dealkylation involved in DNA repair
GO:0008198 IDA ferrous iron binding
GO:0016491 IEA oxidoreductase activity
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0035511 IDA oxidative DNA demethylation
GO:0043734 IDA DNA-N1-methyladenine dioxygenase activity
GO:0051747 IDA cytosine C-5 DNA demethylase activity
GO:0055114 IEA oxidation-reduction process
GO:0070989 TAS oxidative demethylation
GO:0080111 TAS DNA demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059856 alkbh2 alkB, alkylation repair homolog 2 (E. coli) protein_coding Danio_rerio
ENSMUSG00000044339 Alkbh2 alkB, alkylation repair homolog 2 (E. coli) protein_coding Mus_musculus

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