C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, epsilon
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045038 Prkce 10090 + 17:86167785-86657919 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097274 Prkce-003 86168174-86655415 protein_coding
  ENSMUST00000097275 Prkce-001 86167785-86657919 protein_coding
  ENSMUST00000136986 Prkce-005 86493327-86496457 retained_intron
  ENSMUST00000142003 Prkce-002 86167819-86177505 nonsense_mediated_decay
  ENSMUST00000150486 Prkce-004 86490562-86496112 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097274ENSMUST00000097275
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097274 1.164±0.13 1.202±0.14 N/A 58.603±0.00 0.963±0.22 1.488±0.49 0.605±0.02 0.801±0.12 0.304±0.19 2.690±0.36 N/A 1.419±0.88 6.442±1.14 0.225±0.06
ENSMUST00000097275 2.187±0.81 0.974±0.16 2.080±1.19 17.316±13.97 1.365±0.45 1.269±0.25 0.756±0.29 1.664±1.02 0.372±0.25 3.745±1.75 2.193±0.21 1.569±0.93 2.812±1.93 0.200±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001NP CIL_0001NP_0002 CGP 17:85984665-86657919

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002281 IMP macrophage activation involved in immune response
GO:0003785 IDA actin monomer binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004699 IDA calcium-independent protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007155 IEA cell adhesion
GO:0007635 TAS chemosensory behavior
GO:0008047 IEA enzyme activator activity
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0010763 IMP positive regulation of fibroblast migration
GO:0010811 IGI positive regulation of cell-substrate adhesion
GO:0016020 IDA membrane
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019216 IMP regulation of lipid metabolic process
GO:0019899 IEA enzyme binding
GO:0030546 IDA receptor activator activity
GO:0030838 IDA positive regulation of actin filament polymerization
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0032024 IMP positive regulation of insulin secretion
GO:0032230 IMP positive regulation of synaptic transmission, GABAergic
GO:0032467 ISS positive regulation of cytokinesis
GO:0035276 IDA ethanol binding
GO:0035556 IEA intracellular signal transduction
GO:0035641 IGI locomotory exploration behavior
GO:0035669 IMP TRAM-dependent toll-like receptor 4 signaling pathway
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278 IMP response to morphine
GO:0043410 IMP positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050730 IMP regulation of peptidyl-tyrosine phosphorylation
GO:0050996 IMP positive regulation of lipid catabolic process
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0051301 IEA cell division
GO:0061178 IMP regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070257 IMP positive regulation of mucus secretion
GO:0071361 IGI cellular response to ethanol
GO:0071456 IDA cellular response to hypoxia
GO:0071889 IPI 14-3-3 protein binding
GO:0071944 IDA cell periphery
GO:0090303 ISS positive regulation of wound healing
GO:2000273 IDA positive regulation of receptor activity
GO:2001031 IEA positive regulation of cellular glucuronidation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003008 prkcea protein kinase C, epsilon a protein_coding Danio_rerio
ENSDARG00000069928 prkceb protein kinase C, epsilon b protein_coding Danio_rerio
ENSG00000171132 PRKCE protein kinase C, epsilon protein_coding Homo_sapiens

Loading