C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, epsilon
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171132 PRKCE 9606 + 2:45651345-46187990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306156 PRKCE-001 45651774-46187990 protein_coding
  ENST00000394874 PRKCE-008 46000902-46010964 protein_coding
  ENST00000421201 PRKCE-006 45651345-45843034 protein_coding
  ENST00000462720 PRKCE-004 45652360-45701491 processed_transcript
  ENST00000467135 PRKCE-002 45676734-45845758 processed_transcript
  ENST00000469753 PRKCE-013 46073437-46151201 processed_transcript
  ENST00000472021 PRKCE-012 45677025-45686347 processed_transcript
  ENST00000476675 PRKCE-011 45675619-45980356 processed_transcript
  ENST00000480453 PRKCE-010 45652401-45984567 processed_transcript
  ENST00000480633 PRKCE-014 46073796-46151164 processed_transcript
  ENST00000485176 PRKCE-003 45697982-45770860 processed_transcript
  ENST00000489067 PRKCE-007 45978095-45984681 processed_transcript
  ENST00000494472 PRKCE-016 46151102-46160060 processed_transcript
  ENST00000497602 PRKCE-009 45697972-45852026 processed_transcript
  ENST00000498388 PRKCE-015 46151053-46164895 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306156ENST00000394874ENST00000421201ENST00000467135ENST00000480453
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306156 1.728±0.00 1.000±0.00 1.390±0.00 13.264±3.49 1.236±0.31 2.132±0.89 0.446±0.15 1.286±0.00 2.200±0.51 7.467±2.29 0.377±0.13 1.133±0.47 1.788±0.04 1.005±0.00
ENST00000394874 N/A N/A N/A N/A N/A N/A N/A 0.930±0.00 N/A N/A N/A 1.580±0.00 N/A 7.238±0.00
ENST00000421201 N/A N/A N/A N/A N/A N/A N/A 1.410±0.00 N/A N/A N/A N/A N/A N/A
ENST00000467135 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.772±0.61
ENST00000480453 N/A N/A N/A N/A N/A N/A N/A N/A 8.570±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001NP CIL_0001NP_0001 CGP 2:45388680-46187990
CIL_0003T8 CIL_0003T8_0002 CGP 2:45651345-46386703

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002281 IEA macrophage activation involved in immune response
GO:0003785 ISS actin monomer binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004697 IDA:IEA protein kinase C activity
GO:0004699 IEA calcium-independent protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004871 TAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 IDA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0007049 IEA cell cycle
GO:0007155 IEA cell adhesion
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008047 IMP enzyme activator activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010634 IMP positive regulation of epithelial cell migration
GO:0010763 ISS positive regulation of fibroblast migration
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0019216 IEA regulation of lipid metabolic process
GO:0019899 IPI enzyme binding
GO:0030168 TAS platelet activation
GO:0030546 IEA receptor activator activity
GO:0030838 ISS positive regulation of actin filament polymerization
GO:0031663 ISS lipopolysaccharide-mediated signaling pathway
GO:0032024 IEA positive regulation of insulin secretion
GO:0032230 IEA positive regulation of synaptic transmission, GABAergic
GO:0032467 IMP positive regulation of cytokinesis
GO:0035276 IEA ethanol binding
GO:0035556 IEA intracellular signal transduction
GO:0035641 IEA locomotory exploration behavior
GO:0035669 ISS TRAM-dependent toll-like receptor 4 signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278 IEA response to morphine
GO:0043410 IEA positive regulation of MAPK cascade
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050730 IEA regulation of peptidyl-tyrosine phosphorylation
GO:0050996 IEA positive regulation of lipid catabolic process
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0051301 IEA cell division
GO:0061178 IEA regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070257 IEA positive regulation of mucus secretion
GO:0071361 IEA cellular response to ethanol
GO:0071456 IEA cellular response to hypoxia
GO:0071889 IEA 14-3-3 protein binding
GO:0071944 ISS cell periphery
GO:0090303 IMP positive regulation of wound healing
GO:2000273 IEA positive regulation of receptor activity
GO:2000650 TAS negative regulation of sodium ion transmembrane transporter activity
GO:2001031 IMP positive regulation of cellular glucuronidation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003008 prkcea protein kinase C, epsilon a protein_coding Danio_rerio
ENSDARG00000069928 prkceb protein kinase C, epsilon b protein_coding Danio_rerio
ENSMUSG00000045038 Prkce protein kinase C, epsilon protein_coding Mus_musculus

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