Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	OTU deubiquitinase with linear linkage specificity
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000046034	Otulin	10090	-	15:27605919-27630693	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000059662		Otulin-201	27605919-27630693	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000059662	9.158±0.77	24.189±8.64	9.492±2.40	9.528±2.34	15.897±1.05	21.421±4.69	7.710±0.84	16.262±4.28	19.627±10.40	11.882±1.16	7.177±1.26	24.781±6.28	18.956±6.52	6.126±0.93

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0007UF	CIL_0007UF_0002	VISTA	15:27483860-28085186

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0002040	IMP	sprouting angiogenesis
GO:0004843	IDA	ubiquitin-specific protease activity
GO:0005515	IEA	protein binding
GO:0005737	IDA	cytoplasm
GO:0006508	IEA	proteolysis
GO:0008234	IMP	cysteine-type peptidase activity
GO:0032088	ISS	negative regulation of NF-kappaB transcription factor activity
GO:0045087	ISS	innate immune response
GO:0050728	ISS	negative regulation of inflammatory response
GO:0060070	IDA	canonical Wnt signaling pathway
GO:0070431	ISS	nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0071797	IDA	LUBAC complex
GO:1990108	IDA	protein linear deubiquitination

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000073931	fam105ba	family with sequence similarity 105, member B, a	protein_coding	Danio_rerio
ENSDARG00000079886	fam105bb	family with sequence similarity 105, member B	protein_coding	Danio_rerio
ENSG00000154124	OTULIN	OTU deubiquitinase with linear linkage specificity	protein_coding	Homo_sapiens

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