C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: OTU deubiquitinase with linear linkage specificity
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000059662 Otulin-201 ENSMUSG00000046034 10090 - 15:27605919-27630693 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059662
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059662 9.158±0.77 24.189±8.64 9.492±2.40 9.528±2.34 15.897±1.05 21.421±4.69 7.710±0.84 16.262±4.28 19.627±10.40 11.882±1.16 7.177±1.26 24.781±6.28 18.956±6.52 6.126±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UF CIL_0007UF_0002 VISTA 15:27483860-28085186

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002040 IMP sprouting angiogenesis
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 IMP cysteine-type peptidase activity
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0045087 ISS innate immune response
GO:0050728 ISS negative regulation of inflammatory response
GO:0060070 IDA canonical Wnt signaling pathway
GO:0070431 ISS nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0071797 IDA LUBAC complex
GO:1990108 IDA protein linear deubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000284274 OTULIN-001 protein_coding Homo_sapiens 0 1295
ENST00000503023 OTULIN-003 nonsense_mediated_decay Homo_sapiens 0 660
ENST00000507335 OTULIN-002 retained_intron Homo_sapiens 0 291
ENST00000508678 OTULIN-006 retained_intron Homo_sapiens 3e-35 152
ENST00000514913 OTULIN-004 nonsense_mediated_decay Homo_sapiens 0 361

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