C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: melanocortin 4 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047259 Mc4r 10090 - 18:66857715-66860472 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000057942 Mc4r-201 66857715-66860472 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartKidneyLiverOvaryPlacentaTestisENSMUST00000057942
Transcript ID Adipose Bladder Brain Colon Heart Kidney Liver Ovary Placenta Testis
ENSMUST00000057942 0.510±0.10 0.027±0.00 2.038±1.72 0.055±0.03 0.011±0.00 0.088±0.04 0.006±0.00 0.106±0.10 0.013±0.01 0.075±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007FH CIL_0007FH_0002 CGP 18:66458604-66860472

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002024 IEA diet induced thermogenesis
GO:0004977 IDA melanocortin receptor activity
GO:0004980 IDA melanocyte-stimulating hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006112 IEA energy reserve metabolic process
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007631 IMP feeding behavior
GO:0016021 IEA integral component of membrane
GO:0017046 IEA peptide hormone binding
GO:0019222 IMP regulation of metabolic process
GO:0030073 IGI insulin secretion
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032868 IMP response to insulin
GO:0042923 IEA neuropeptide binding
GO:0045780 IMP positive regulation of bone resorption
GO:0060259 IEA regulation of feeding behavior
GO:2000252 IEA negative regulation of feeding behavior
GO:2000821 IEA regulation of grooming behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015515 mc4r melanocortin 4 receptor protein_coding Danio_rerio
ENSG00000166603 MC4R melanocortin 4 receptor protein_coding Homo_sapiens

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