C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048583 Igf2 10090 - 7:142650766-142666816 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000033 Igf2-001 142650766-142657496 protein_coding
  ENSMUST00000097936 Igf2-201 142650769-142657466 protein_coding
  ENSMUST00000105935 Igf2-004 142653756-142666816 protein_coding
  ENSMUST00000105936 Igf2-003 142650769-142661305 protein_coding
  ENSMUST00000121128 Igf2-002 142650769-142659489 protein_coding
  ENSMUST00000143666 Igf2-006 142655442-142661205 retained_intron
  ENSMUST00000145896 Igf2-005 142654049-142661870 protein_coding
  ENSMUST00000163148 Igf2-008 142650843-142653030 processed_transcript
  ENSMUST00000178921 Igf2-007 142654352-142656018 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000033ENSMUST00000097936ENSMUST00000105935ENSMUST00000105936ENSMUST00000121128ENSMUST00000163148
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000033 N/A 0.964±0.14 N/A 16.650±11.29 0.377±0.00 0.530±0.15 1.605±0.50 0.959±0.13 213.659±210.11 N/A N/A 1.121±0.33 244.807±69.30 0.961±0.00
ENSMUST00000097936 1.057±0.00 0.741±0.00 N/A N/A 0.776±0.18 0.686±0.24 2.206±0.08 0.776±0.00 0.071±0.03 0.813±0.00 1.521±0.55 1.633±0.31 187.437±62.92 N/A
ENSMUST00000105935 4.517±0.00 3.530±1.54 N/A N/A 3.322±0.48 1.568±0.28 N/A 5.954±1.28 0.183±0.08 2.954±0.24 N/A 5.332±1.54 N/A 1.999±0.00
ENSMUST00000105936 N/A N/A 0.609±0.00 N/A 0.326±0.10 0.325±0.05 1.724±0.41 0.595±0.01 N/A N/A 0.766±0.37 0.880±0.16 N/A N/A
ENSMUST00000121128 0.411±0.02 0.282±0.04 1.037±0.21 9.568±8.07 0.214±0.04 0.264±0.14 1.254±0.15 N/A 90.318±20.06 0.443±0.08 1.017±0.00 0.474±0.13 89.511±45.08 0.224±0.12
ENSMUST00000163148 5.457±0.77 7.329±1.17 3.675±0.00 42.592±8.63 4.816±1.32 3.810±0.37 10.519±1.49 7.306±1.11 161.728±264.28 4.344±0.68 N/A 9.996±3.24 399.589±21.53 1.694±0.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0002 VISTA 7:142247512-142849546
CIL_0007RG CIL_0007RG_0002 VISTA 7:142251566-142854813
CIL_00097V CIL_00097V_0002 VISTA 7:142268912-142873912
CIL_0005N8 CIL_0005N8_0003 CGP 7:142532799-142666816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEP osteoblast differentiation
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0005158 IEA insulin receptor binding
GO:0005159 IPI insulin-like growth factor receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0006006 IEA glucose metabolic process
GO:0007565 IEA female pregnancy
GO:0007613 IEA memory
GO:0008083 IEA growth factor activity
GO:0009314 IEA response to radiation
GO:0009887 IMP organ morphogenesis
GO:0014070 IEA response to organic cyclic compound
GO:0030546 IMP receptor activator activity
GO:0031017 IMP exocrine pancreas development
GO:0031667 IEA response to nutrient levels
GO:0032355 IEA response to estradiol
GO:0035094 IEA response to nicotine
GO:0038028 IMP insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0042060 IEA wound healing
GO:0042104 IEA positive regulation of activated T cell proliferation
GO:0042493 IEA response to drug
GO:0043085 IMP positive regulation of catalytic activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043539 IMP protein serine/threonine kinase activator activity
GO:0045471 IEA response to ethanol
GO:0045725 IMP positive regulation of glycogen biosynthetic process
GO:0045840 IEA positive regulation of mitosis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046628 IMP positive regulation of insulin receptor signaling pathway
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051146 IGI striated muscle cell differentiation
GO:0051781 IEA positive regulation of cell division
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071902 IMP positive regulation of protein serine/threonine kinase activity
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process
GO:2000273 IMP positive regulation of receptor activity
GO:2000467 IMP positive regulation of glycogen (starch) synthase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018643 igf2a insulin-like growth factor 2a protein_coding Danio_rerio
ENSDARG00000033307 igf2b insulin-like growth factor 2b protein_coding Danio_rerio
ENSG00000167244 IGF2 insulin-like growth factor 2 protein_coding Homo_sapiens

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