C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000121128 Igf2-002 ENSMUSG00000048583 10090 - 7:142650769-142659489 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000121128
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000121128 0.411±0.02 0.282±0.04 1.037±0.21 9.568±8.07 0.214±0.04 0.264±0.14 1.254±0.15 90.318±20.06 0.443±0.08 1.017±0.00 0.474±0.13 89.511±45.08 0.224±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0002 VISTA 7:142247512-142849546
CIL_0007RG CIL_0007RG_0002 VISTA 7:142251566-142854813
CIL_00097V CIL_00097V_0002 VISTA 7:142268912-142873912
CIL_0005N8 CIL_0005N8_0003 CGP 7:142532799-142666816

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001649 IEP osteoblast differentiation
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0005158 IEA insulin receptor binding
GO:0005159 IPI insulin-like growth factor receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0006006 IEA glucose metabolic process
GO:0007565 IEA female pregnancy
GO:0007613 IEA memory
GO:0008083 IEA growth factor activity
GO:0009314 IEA response to radiation
GO:0009887 IMP organ morphogenesis
GO:0014070 IEA response to organic cyclic compound
GO:0030546 IMP receptor activator activity
GO:0031017 IMP exocrine pancreas development
GO:0031667 IEA response to nutrient levels
GO:0032355 IEA response to estradiol
GO:0035094 IEA response to nicotine
GO:0038028 IMP insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0042060 IEA wound healing
GO:0042104 IEA positive regulation of activated T cell proliferation
GO:0042493 IEA response to drug
GO:0043085 IMP positive regulation of catalytic activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043539 IMP protein serine/threonine kinase activator activity
GO:0045471 IEA response to ethanol
GO:0045725 IMP positive regulation of glycogen biosynthetic process
GO:0045840 IEA positive regulation of mitosis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046628 IMP positive regulation of insulin receptor signaling pathway
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051146 IGI striated muscle cell differentiation
GO:0051781 IEA positive regulation of cell division
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071902 IMP positive regulation of protein serine/threonine kinase activity
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process
GO:2000273 IMP positive regulation of receptor activity
GO:2000467 IMP positive regulation of glycogen (starch) synthase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000300632 IGF2-201 protein_coding Homo_sapiens 0 662
ENST00000356578 INS-IGF2-002 nonsense_mediated_decay Homo_sapiens 0 662
ENST00000381389 IGF2-009 protein_coding Homo_sapiens 0 662
ENST00000381392 IGF2-004 protein_coding Homo_sapiens 0 619
ENST00000381395 IGF2-003 protein_coding Homo_sapiens 0 662
ENST00000381406 IGF2-002 protein_coding Homo_sapiens 0 1214
ENST00000416167 IGF2-001 protein_coding Homo_sapiens 0 1690
ENST00000418738 IGF2-005 protein_coding Homo_sapiens 0 662
ENST00000434045 IGF2-007 protein_coding Homo_sapiens 0 662

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