C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LEM domain containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048661 Lemd3 10090 - 10:120923413-120979332 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000119093 Lemd3-002 120923852-120979332 protein_coding
  ENSMUST00000119944 Lemd3-001 120923413-120979332 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000119093ENSMUST00000119944
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000119093 1.947±0.83 2.306±0.68 N/A 6.273±0.00 2.194±1.64 4.091±1.46 1.193±0.36 1.135±0.42 0.889±0.51 3.134±0.53 N/A 5.460±0.95 5.088±0.50 3.116±0.61
ENSMUST00000119944 1.212±0.27 2.064±0.00 4.085±0.39 5.906±3.30 0.872±0.14 N/A 0.827±0.50 1.660±0.45 1.926±0.90 1.622±0.48 2.396±0.28 2.593±1.44 4.461±1.99 1.464±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Y5 CIL_0006Y5_0002 CGP 10:120781096-120979332
CIL_0006XX CIL_0006XX_0002 CGP 10:120923413-121100650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001525 IMP angiogenesis
GO:0002044 IMP blood vessel endothelial cell migration involved in intussusceptive angiogenesis
GO:0005515 IEA protein binding
GO:0005635 IDA nuclear envelope
GO:0005637 IEA nuclear inner membrane
GO:0005639 IEA integral component of nuclear inner membrane
GO:0006997 IMP nucleus organization
GO:0016021 ISA integral component of membrane
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IEA negative regulation of BMP signaling pathway
GO:0032926 IEA negative regulation of activin receptor signaling pathway
GO:0035914 IMP skeletal muscle cell differentiation
GO:0051726 IMP regulation of cell cycle
GO:1903053 IMP regulation of extracellular matrix organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015824 lemd3 LEM domain containing 3 protein_coding Danio_rerio
ENSG00000174106 LEMD3 LEM domain containing 3 protein_coding Homo_sapiens

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