C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-hydroxytryptamine (serotonin) receptor 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049511 Htr1b 10090 - 9:81628291-81633828 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051005 Htr1b-201 81631343-81632615 protein_coding
  ENSMUST00000183482 Htr1b-002 81628291-81633828 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051005ENSMUST00000183482
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051005 N/A 0.149±0.02 N/A N/A 0.036±0.02 0.038±0.00 0.025±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000183482 0.120±0.11 0.156±0.02 0.232±0.03 0.444±0.16 0.036±0.01 0.083±0.05 0.037±0.00 0.146±0.01 0.007±0.00 0.205±0.02 0.016±0.00 0.237±0.16 0.058±0.02 0.094±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PU CIL_0006PU_0002 CGP 9:80313330-81633828
CIL_0006GC CIL_0006GC_0002 CGP 9:81628291-82206007

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002031 IDA G-protein coupled receptor internalization
GO:0004993 IDA serotonin receptor activity
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007198 ISS adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007205 IMP protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007631 IEA feeding behavior
GO:0008144 IDA drug binding
GO:0014059 IEA regulation of dopamine secretion
GO:0014063 IMP negative regulation of serotonin secretion
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0035690 ISS cellular response to drug
GO:0042220 IEA response to cocaine
GO:0042310 IEA vasoconstriction
GO:0042493 IDA response to drug
GO:0042756 IEA drinking behavior
GO:0045471 IEA response to ethanol
GO:0046849 IGI bone remodeling
GO:0050795 IEA regulation of behavior
GO:0051378 IDA serotonin binding
GO:0051385 IEA response to mineralocorticoid
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0071312 ISS cellular response to alkaloid
GO:0071502 IDA cellular response to temperature stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053987 htr1b 5-hydroxytryptamine (serotonin) receptor 1B protein_coding Danio_rerio
ENSG00000135312 HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled protein_coding Homo_sapiens

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