C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ORAI calcium release-activated calcium modulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049686 Orai1 10090 + 5:123015074-123030450 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051016 Orai1-201 123015074-123030156 protein_coding
  ENSMUST00000121652 Orai1-001 123015074-123030450 protein_coding
  ENSMUST00000152213 Orai1-002 123015338-123029465 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051016ENSMUST00000121652
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051016 20.204±1.91 17.861±3.95 21.977±0.25 39.554±4.03 38.111±2.99 12.738±1.92 25.282±5.68 10.886±1.84 40.579±3.79 13.992±3.62 24.138±4.43 17.320±8.45 32.623±2.68
ENSMUST00000121652 4.810±0.00 N/A N/A 9.929±1.41 N/A 4.152±0.36 7.653±0.66 4.046±0.90 7.765±0.73 4.685±0.18 5.691±0.62 7.218±2.15 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G4 CIL_0007G4_0003 CGP 5:122850188-123015080
CIL_0007G5 CIL_0007G5_0004 CGP 5:122870668-123030450
CIL_0007G6 CIL_0007G6_0003 CGP 5:123015074-123047016

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002115 IGI store-operated calcium entry
GO:0002376 IEA immune system process
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005887 ISS integral component of plasma membrane
GO:0015279 ISS store-operated calcium channel activity
GO:0016020 IDA membrane
GO:0042802 IEA identical protein binding
GO:0043234 IPI protein complex
GO:0051924 IEA regulation of calcium ion transport
GO:0051928 ISS positive regulation of calcium ion transport
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004154 orai1b ORAI calcium release-activated calcium modulator 1b protein_coding Danio_rerio
ENSDARG00000011515 ORAI1 (2 of 2) ORAI calcium release-activated calcium modulator 1 protein_coding Danio_rerio
ENSG00000276045 ORAI1 ORAI calcium release-activated calcium modulator 1 protein_coding Homo_sapiens

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