C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RPTOR independent companion of MTOR, complex 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050310 Rictor 10090 + 15:6708381-6800398 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061656 Rictor-201 6708381-6800398 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061656
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061656 4.891±1.37 3.174±1.13 3.586±0.88 4.751±1.41 4.922±1.59 3.417±1.11 1.519±0.24 2.955±0.54 2.701±1.29 6.047±0.68 0.719±0.15 5.808±1.52 3.238±1.05 2.114±1.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CX CIL_0003CX_0002 CGP 15:6579871-6800398
CIL_0006DN CIL_0006DN_0002 CGP 15:6708381-6874969

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005515 IPI protein binding
GO:0009790 IMP embryo development
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0031532 ISS actin cytoskeleton reorganization
GO:0031929 IEA TOR signaling
GO:0031932 IDA TORC2 complex
GO:0032008 IEA positive regulation of TOR signaling
GO:0032314 IMP regulation of Rac GTPase activity
GO:0032956 IEA regulation of actin cytoskeleton organization
GO:0042325 IEA regulation of phosphorylation
GO:0043022 IDA ribosome binding
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051896 IDA regulation of protein kinase B signaling
GO:0051897 IEA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002020 rictorb rapamycin-insensitive companion of mTOR b protein_coding Danio_rerio
ENSDARG00000059414 rictora rapamycin-insensitive companion of mTOR a protein_coding Danio_rerio
ENSDARG00000059418 RICTOR (3 of 3) RPTOR independent companion of MTOR, complex 2 protein_coding Danio_rerio
ENSG00000164327 RICTOR RPTOR independent companion of MTOR, complex 2 protein_coding Homo_sapiens

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