C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RPTOR independent companion of MTOR, complex 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000061656 Rictor-201 ENSMUSG00000050310 10090 + 15:6708381-6800398 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061656
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061656 4.891±1.37 3.174±1.13 3.586±0.88 4.751±1.41 4.922±1.59 3.417±1.11 1.519±0.24 2.955±0.54 2.701±1.29 6.047±0.68 0.719±0.15 5.808±1.52 3.238±1.05 2.114±1.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CX CIL_0003CX_0002 CGP 15:6579871-6800398
CIL_0006DN CIL_0006DN_0002 CGP 15:6708381-6874969

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005515 IPI protein binding
GO:0009790 IMP embryo development
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0031532 ISS actin cytoskeleton reorganization
GO:0031929 IEA TOR signaling
GO:0031932 IDA TORC2 complex
GO:0032008 IEA positive regulation of TOR signaling
GO:0032314 IMP regulation of Rac GTPase activity
GO:0032956 IEA regulation of actin cytoskeleton organization
GO:0042325 IEA regulation of phosphorylation
GO:0043022 IDA ribosome binding
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051896 IDA regulation of protein kinase B signaling
GO:0051897 IEA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000296782 RICTOR-002 protein_coding Homo_sapiens 0 5217
ENST00000357387 RICTOR-001 protein_coding Homo_sapiens 0 6608
ENST00000503698 RICTOR-009 processed_transcript Homo_sapiens 0 695
ENST00000505927 RICTOR-010 retained_intron Homo_sapiens 0 316
ENST00000509567 RICTOR-007 processed_transcript Homo_sapiens 0 643
ENST00000510711 RICTOR-005 retained_intron Homo_sapiens 0 1291
ENST00000511516 RICTOR-003 nonsense_mediated_decay Homo_sapiens 0 5432
ENST00000513566 RICTOR-004 retained_intron Homo_sapiens 0 1160
ENST00000514735 RICTOR-006 protein_coding Homo_sapiens 0 907
ENST00000515846 RICTOR-008 retained_intron Homo_sapiens 0 481

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