C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050552 Lamtor4 10090 + 5:138255608-138259398 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062067 Lamtor4-001 138255608-138259395 protein_coding
  ENSMUST00000160157 Lamtor4-002 138255831-138259398 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062067ENSMUST00000160157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062067 160.044±32.45 126.617±60.06 70.969±5.42 54.254±11.50 100.987±40.93 127.190±10.76 83.542±11.14 222.691±14.82 86.319±38.30 96.920±3.15 40.571±3.06 113.782±36.01 41.989±18.09 14.788±4.43
ENSMUST00000160157 N/A N/A 6.650±0.00 7.239±2.83 6.359±0.00 N/A N/A N/A 4.281±0.00 N/A N/A 4.732±0.20 2.966±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QI CIL_0008QI_0002 VISTA 5:137705744-138314172
CIL_0002JK CIL_0002JK_0002 CGP 5:138255608-138264046

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005764 ISS lysosome
GO:0008361 ISS regulation of cell size
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043547 ISS positive regulation of GTPase activity
GO:0061462 ISS protein localization to lysosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045542 LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 protein_coding Danio_rerio
ENSG00000188186 LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 protein_coding Homo_sapiens

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