C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062067 Lamtor4-001 ENSMUSG00000050552 10090 + 5:138255608-138259395 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062067
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062067 160.044±32.45 126.617±60.06 70.969±5.42 54.254±11.50 100.987±40.93 127.190±10.76 83.542±11.14 222.691±14.82 86.319±38.30 96.920±3.15 40.571±3.06 113.782±36.01 41.989±18.09 14.788±4.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QI CIL_0008QI_0002 VISTA 5:137705744-138314172
CIL_0002JK CIL_0002JK_0002 CGP 5:138255608-138264046

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005764 ISS lysosome
GO:0008361 ISS regulation of cell size
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043547 ISS positive regulation of GTPase activity
GO:0061462 ISS protein localization to lysosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000341942 LAMTOR4-001 protein_coding Homo_sapiens 0 424
ENST00000441173 LAMTOR4-005 protein_coding Homo_sapiens 0 257
ENST00000460732 LAMTOR4-003 protein_coding Homo_sapiens 0 346
ENST00000466498 LAMTOR4-011 protein_coding Homo_sapiens 0 289
ENST00000468582 LAMTOR4-007 protein_coding Homo_sapiens 0 390
ENST00000488241 LAMTOR4-008 protein_coding Homo_sapiens 0 316

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