C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS related protein 1b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052681 Rap1b 10090 - 10:117814471-117845935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064667 Rap1b-201 117814471-117845935 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064667
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064667 36.682±5.19 57.071±15.49 28.640±6.07 24.017±7.11 44.691±4.80 47.314±8.09 19.715±2.58 28.750±8.84 26.442±12.21 55.499±21.19 6.848±1.09 63.521±40.69 52.722±15.51 9.922±2.53

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 ISS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 ISS GTP binding
GO:0005737 IEA cytoplasm
GO:0005811 IEA lipid particle
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0006184 IEA GTP catabolic process
GO:0007264 IDA small GTPase mediated signal transduction
GO:0008283 IPI cell proliferation
GO:0019003 ISS GDP binding
GO:0032403 ISO protein complex binding
GO:0032486 ISS Rap protein signal transduction
GO:0045955 IGI negative regulation of calcium ion-dependent exocytosis
GO:0061028 ISS establishment of endothelial barrier
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IGI positive regulation of ERK1 and ERK2 cascade
GO:0071320 ISS cellular response to cAMP
GO:1901888 ISS regulation of cell junction assembly
GO:2000114 ISS regulation of establishment of cell polarity
GO:2000301 IGI negative regulation of synaptic vesicle exocytosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008867 rap1b RAS related protein 1b protein_coding Danio_rerio
ENSG00000127314 RAP1B RAP1B, member of RAS oncogene family protein_coding Homo_sapiens

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