C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053113 Socs3 10090 - 11:117966079-117970047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054002 Socs3-001 117966079-117969186 protein_coding
  ENSMUST00000123255 Socs3-002 117968875-117970047 processed_transcript
  ENSMUST00000132295 Socs3-003 117968934-117969451 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054002
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054002 3.916±2.69 4.741±0.46 3.294±1.19 2.202±1.61 9.259±5.07 6.397±1.84 1.219±0.42 1.483±0.59 3.414±1.71 11.521±4.65 1.242±0.53 11.353±3.29 9.602±3.33 0.250±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YS CIL_0007YS_0002 VISTA 11:117565410-118167678
CIL_00049Y CIL_00049Y_0002 CGP 11:117867952-117970047
CIL_0003UD CIL_0003UD_0003 CGP 11:117966079-118024011

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001932 IDA regulation of protein phosphorylation
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0007259 IEA JAK-STAT cascade
GO:0009968 IGI negative regulation of signal transduction
GO:0016567 IEA protein ubiquitination
GO:0040008 IEA regulation of growth
GO:0043066 IEA negative regulation of apoptotic process
GO:0045595 IGI regulation of cell differentiation
GO:0045597 IDA positive regulation of cell differentiation
GO:0046627 IDA negative regulation of insulin receptor signaling pathway
GO:0050728 IGI negative regulation of inflammatory response
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0060674 IMP placenta blood vessel development
GO:0060707 IGI trophoblast giant cell differentiation
GO:0060708 IGI spongiotrophoblast differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025428 socs3a suppressor of cytokine signaling 3a protein_coding Danio_rerio
ENSDARG00000026611 socs3b suppressor of cytokine signaling 3b protein_coding Danio_rerio
ENSG00000184557 SOCS3 suppressor of cytokine signaling 3 protein_coding Homo_sapiens

Loading