C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DAN domain family, member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053226 Dand5 10090 - 8:84815405-84822823 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065539 Dand5-201 84815405-84822823 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065539
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065539 2.019±0.18 4.224±0.07 2.057±0.00 3.053±0.31 1.357±0.59 1.839±0.46 2.795±0.77 2.270±0.25 1.580±0.46 1.639±0.18 5.730±0.42 2.885±2.02 2.092±1.17 16.673±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZV CIL_0007ZV_0002 VISTA 8:84428902-85032705
CIL_0007VV CIL_0007VV_0002 VISTA 8:84441926-85045230

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003140 IMP determination of left/right asymmetry in lateral mesoderm
GO:0003281 IMP ventricular septum development
GO:0003283 IMP atrial septum development
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0007368 IGI determination of left/right symmetry
GO:0016015 IMP morphogen activity
GO:0017015 IDA regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0038101 IDA sequestering of nodal from receptor via nodal binding
GO:0061371 IMP determination of heart left/right asymmetry
GO:1900108 IDA negative regulation of nodal signaling pathway
GO:1900146 ISS negative regulation of nodal signaling pathway involved in determination of left/right asymmetry
GO:1900164 NAS nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036471 dand5 DAN domain family, member 5 protein_coding Danio_rerio
ENSG00000179284 DAND5 DAN domain family member 5, BMP antagonist protein_coding Homo_sapiens

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