C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DAN domain family member 5, BMP antagonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179284 DAND5 9606 + 19:12965159-12974762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317060 DAND5-001 12969482-12974762 protein_coding
  ENST00000585548 DAND5-002 12965159-12974524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317060ENST00000585548
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317060 N/A N/A N/A 0.143±0.00 0.979±0.00 1.299±0.95 0.473±0.00 N/A 0.132±0.00 N/A 0.120±0.00 N/A 0.468±0.00
ENST00000585548 0.181±0.00 0.498±0.00 0.199±0.17 0.247±0.21 0.108±0.00 0.955±0.00 N/A 0.053±0.00 0.119±0.03 0.113±0.00 0.138±0.08 0.090±0.06 0.219±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VV CIL_0007VV_0001 VISTA 19:12752697-13356541
CIL_0007ZV CIL_0007ZV_0001 VISTA 19:12767682-13372012
CIL_0001IU CIL_0001IU_0002 CGP 19:12965159-13098796

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003140 ISS determination of left/right asymmetry in lateral mesoderm
GO:0003281 ISS ventricular septum development
GO:0003283 ISS atrial septum development
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0007368 IEA determination of left/right symmetry
GO:0016015 ISS morphogen activity
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 ISS negative regulation of BMP signaling pathway
GO:0038101 ISS sequestering of nodal from receptor via nodal binding
GO:0061371 ISS determination of heart left/right asymmetry
GO:1900108 ISS negative regulation of nodal signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036471 dand5 DAN domain family, member 5 protein_coding Danio_rerio
ENSMUSG00000053226 Dand5 DAN domain family, member 5 protein_coding Mus_musculus

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