C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 3-phosphoglycerate dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053398 Phgdh 10090 - 3:98313170-98339990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065793 Phgdh-001 98313170-98339990 protein_coding
  ENSMUST00000148488 Phgdh-002 98321325-98337548 protein_coding
  ENSMUST00000152106 Phgdh-004 98321218-98328613 retained_intron
  ENSMUST00000153694 Phgdh-003 98320683-98333570 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065793ENSMUST00000148488ENSMUST00000153694
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065793 109.938±62.46 11.214±3.87 5.663±1.44 35.805±9.57 43.886±15.15 11.396±1.85 1.114±0.38 17.658±2.18 44.042±47.42 8.902±1.10 0.928±0.66 33.479±12.61 70.297±57.83 7.677±1.77
ENSMUST00000148488 N/A N/A N/A 85.388±0.00 N/A N/A N/A N/A N/A N/A 0.447±0.00 46.061±31.21 108.820±62.88 26.651±30.88
ENSMUST00000153694 N/A N/A N/A N/A N/A N/A N/A N/A 0.324±0.00 N/A N/A 5.036±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004617 TAS phosphoglycerate dehydrogenase activity
GO:0006541 IMP glutamine metabolic process
GO:0006544 IMP glycine metabolic process
GO:0006563 IMP L-serine metabolic process
GO:0006564 IEA L-serine biosynthetic process
GO:0006566 IMP threonine metabolic process
GO:0009448 IMP gamma-aminobutyric acid metabolic process
GO:0010468 IMP regulation of gene expression
GO:0019530 IMP taurine metabolic process
GO:0021510 IMP spinal cord development
GO:0021782 IMP glial cell development
GO:0021915 IMP neural tube development
GO:0022008 IMP neurogenesis
GO:0031175 IMP neuron projection development
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:0070314 IMP G1 to G0 transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001873 phgdh phosphoglycerate dehydrogenase protein_coding Danio_rerio
ENSG00000092621 PHGDH phosphoglycerate dehydrogenase protein_coding Homo_sapiens

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