C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoglycerate dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092621 PHGDH 9606 + 1:119659798-119744215 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369407 PHGDH-002 119719627-119744213 protein_coding
  ENST00000369409 PHGDH-001 119711887-119744215 protein_coding
  ENST00000462324 PHGDH-005 119711906-119730071 processed_transcript
  ENST00000469443 PHGDH-007 119734304-119735429 processed_transcript
  ENST00000482968 PHGDH-003 119739462-119744213 processed_transcript
  ENST00000493622 PHGDH-006 119659798-119734676 processed_transcript
  ENST00000496756 PHGDH-004 119711884-119721495 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369407ENST00000369409ENST00000469443
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369407 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.741±0.00
ENST00000369409 7.472±0.00 20.082±0.00 6.040±0.00 50.334±31.16 31.677±30.83 10.278±7.57 1.347±0.71 22.356±5.14 17.711±9.82 6.262±4.58 1.142±0.60 37.130±27.27 18.872±7.74 47.525±17.53
ENST00000469443 N/A N/A N/A N/A N/A N/A 0.593±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004617 IEA phosphoglycerate dehydrogenase activity
GO:0005829 TAS cytosol
GO:0006541 IEA glutamine metabolic process
GO:0006544 IEA glycine metabolic process
GO:0006563 IEA L-serine metabolic process
GO:0006564 IEA L-serine biosynthetic process
GO:0006566 IEA threonine metabolic process
GO:0007420 TAS brain development
GO:0008152 IEA metabolic process
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0009055 TAS electron carrier activity
GO:0009448 IEA gamma-aminobutyric acid metabolic process
GO:0010468 IEA regulation of gene expression
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019530 IEA taurine metabolic process
GO:0021510 IEA spinal cord development
GO:0021782 IEA glial cell development
GO:0021915 IEA neural tube development
GO:0022008 IEA neurogenesis
GO:0031175 IEA neuron projection development
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070314 IEA G1 to G0 transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001873 phgdh phosphoglycerate dehydrogenase protein_coding Danio_rerio
ENSMUSG00000053398 Phgdh 3-phosphoglycerate dehydrogenase protein_coding Mus_musculus

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