C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: 3-phosphoglycerate dehydrogenase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000065793 Phgdh-001 ENSMUSG00000053398 10090 - 3:98313170-98339990 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065793
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065793 109.938±62.46 11.214±3.87 5.663±1.44 35.805±9.57 43.886±15.15 11.396±1.85 1.114±0.38 17.658±2.18 44.042±47.42 8.902±1.10 0.928±0.66 33.479±12.61 70.297±57.83 7.677±1.77

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004617 TAS phosphoglycerate dehydrogenase activity
GO:0006541 IMP glutamine metabolic process
GO:0006544 IMP glycine metabolic process
GO:0006563 IMP L-serine metabolic process
GO:0006564 IEA L-serine biosynthetic process
GO:0006566 IMP threonine metabolic process
GO:0009448 IMP gamma-aminobutyric acid metabolic process
GO:0010468 IMP regulation of gene expression
GO:0019530 IMP taurine metabolic process
GO:0021510 IMP spinal cord development
GO:0021782 IMP glial cell development
GO:0021915 IMP neural tube development
GO:0022008 IMP neurogenesis
GO:0031175 IMP neuron projection development
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:0070314 IMP G1 to G0 transition

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369407 PHGDH-002 protein_coding Homo_sapiens 0 1751
ENST00000369409 PHGDH-001 protein_coding Homo_sapiens 0 1949
ENST00000462324 PHGDH-005 processed_transcript Homo_sapiens 0 483
ENST00000482968 PHGDH-003 processed_transcript Homo_sapiens 0 743
ENST00000493622 PHGDH-006 processed_transcript Homo_sapiens 0 505
ENST00000496756 PHGDH-004 processed_transcript Homo_sapiens 0 396

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