C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukemia inhibitory factor receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000171588 Lifr-203 ENSMUSG00000054263 10090 + 15:7154353-7197489 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENSMUST00000171588
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000171588 6.404±0.00 1.800±0.20 5.403±1.03 0.573±0.23 4.212±2.10 0.790±0.13 10.803±6.65 9.528±0.00 3.576±1.41 3.023±1.45 12.562±4.09 0.379±0.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000688 CIL_000688_0002 CGP 15:6813577-7197489
CIL_0008W3 CIL_0008W3_0002 VISTA 15:7122223-7723664

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004897 IEA ciliary neurotrophic factor receptor activity
GO:0004923 IEA leukemia inhibitory factor receptor activity
GO:0004924 IEA oncostatin-M receptor activity
GO:0005127 IEA ciliary neurotrophic factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005886 IEA plasma membrane
GO:0008284 IGI positive regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019838 IEA growth factor binding
GO:0034097 IEA response to cytokine
GO:0038165 IEA oncostatin-M-mediated signaling pathway
GO:0048861 IEA leukemia inhibitory factor signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0070120 IEA ciliary neurotrophic factor-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263409 LIFR-001 protein_coding Homo_sapiens 0 2427
ENST00000453190 LIFR-003 protein_coding Homo_sapiens 0 2379
ENST00000503088 LIFR-002 processed_transcript Homo_sapiens 0 1059
ENST00000506003 LIFR-007 nonsense_mediated_decay Homo_sapiens 2e-23 113

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