C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000171904 Kcnn4-201 ENSMUSG00000054342 10090 + 7:24370263-24385209 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000171904
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000171904 1.767±0.62 0.793±0.11 16.009±3.86 0.154±0.05 10.525±4.60 32.298±10.78 0.283±0.20 0.779±0.43 29.639±33.71 2.415±0.87 0.143±0.06 4.029±1.71 1.101±0.86 0.441±0.24

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005267 IGI potassium channel activity
GO:0005515 IEA protein binding
GO:0005516 IBA calmodulin binding
GO:0005886 IBA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006816 IEA calcium ion transport
GO:0006820 IEA anion transport
GO:0006884 IMP cell volume homeostasis
GO:0015269 IDA calcium-activated potassium channel activity
GO:0016286 IEA small conductance calcium-activated potassium channel activity
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019903 IEA protein phosphatase binding
GO:0022894 IBA Intermediate conductance calcium-activated potassium channel activity
GO:0030322 IEA stabilization of membrane potential
GO:0043025 IBA neuronal cell body
GO:0045121 IEA membrane raft
GO:0045332 IMP phospholipid translocation
GO:0046541 IGI saliva secretion
GO:0050714 IDA positive regulation of protein secretion
GO:0050862 IEA positive regulation of T cell receptor signaling pathway
GO:0071435 IEA potassium ion export

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000222249 KCNN1-001 protein_coding Homo_sapiens 2e-35 156
ENST00000262888 KCNN4-001 protein_coding Homo_sapiens 0 1563
ENST00000597184 KCNN4-012 retained_intron Homo_sapiens 0 239
ENST00000598836 KCNN4-010 protein_coding Homo_sapiens 0 233
ENST00000599107 KCNN4-008 retained_intron Homo_sapiens 0 523
ENST00000599720 KCNN4-007 nonsense_mediated_decay Homo_sapiens 0 636
ENST00000600408 KCNN4-009 nonsense_mediated_decay Homo_sapiens 0 219
ENST00000600909 KCNN4-013 protein_coding Homo_sapiens 4e-32 143
ENST00000601549 KCNN4-011 retained_intron Homo_sapiens 0 239
ENST00000615047 KCNN4-201 protein_coding Homo_sapiens 0 881
ENST00000615435 KCNN1-201 protein_coding Homo_sapiens 8e-36 156

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