C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transformed mouse 3T3 cell double minute 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054387 Mdm4 10090 - 1:132959484-133030561 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067398 Mdm4-003 132991354-133025356 protein_coding
  ENSMUST00000067429 Mdm4-005 132989845-133025348 protein_coding
  ENSMUST00000185398 Mdm4-004 132991227-133025354 nonsense_mediated_decay
  ENSMUST00000185418 Mdm4-010 133009097-133025330 retained_intron
  ENSMUST00000186513 Mdm4-008 132999472-133001421 retained_intron
  ENSMUST00000186617 Mdm4-006 132959484-133025338 protein_coding
  ENSMUST00000186645 Mdm4-007 133017701-133025338 retained_intron
  ENSMUST00000187244 Mdm4-014 132961653-132972713 processed_transcript
  ENSMUST00000187529 Mdm4-013 133001170-133004128 retained_intron
  ENSMUST00000188090 Mdm4-001 132986220-133025416 protein_coding
  ENSMUST00000189596 Mdm4-012 132996644-133004325 retained_intron
  ENSMUST00000190312 Mdm4-011 132996641-133018858 processed_transcript
  ENSMUST00000190807 Mdm4-009 133009151-133030561 protein_coding
  ENSMUST00000191212 Mdm4-002 132990402-133025357 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067398ENSMUST00000188090
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067398 N/A N/A 6.884±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 9.266±2.40 39.859±0.00
ENSMUST00000188090 12.467±9.16 30.520±8.85 22.318±14.12 9.640±4.38 3.127±0.00 5.378±2.24 3.080±0.91 14.448±6.19 9.855±4.83 3.951±1.43 12.581±11.06 11.708±6.54 9.188±5.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084Z CIL_00084Z_0002 VISTA 1:132779893-133380922
CIL_00056L CIL_00056L_0002 CGP 1:132880273-133030561

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006461 IEA protein complex assembly
GO:0008270 IEA zinc ion binding
GO:0008283 ISS cell proliferation
GO:0008284 IMP positive regulation of cell proliferation
GO:0019899 IEA enzyme binding
GO:0030330 ISS DNA damage response, signal transduction by p53 class mediator
GO:0042177 ISS negative regulation of protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0045023 ISS G0 to G1 transition
GO:0050821 IEA protein stabilization
GO:0071157 IEA negative regulation of cell cycle arrest
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057513 mdm4 transformed 3T3 cell double minute 4 homolog (mouse) protein_coding Danio_rerio
ENSG00000198625 MDM4 MDM4, p53 regulator protein_coding Homo_sapiens

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