C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MDM4, p53 regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198625 MDM4 9606 + 1:204516379-204558120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367179 MDM4-006 204537857-204549194 protein_coding
  ENST00000367180 MDM4-009 204525490-204537041 protein_coding
  ENST00000367182 MDM4-001 204516383-204558120 protein_coding
  ENST00000367183 MDM4-201 204516379-204558119 protein_coding
  ENST00000391947 MDM4-202 204516379-204558119 protein_coding
  ENST00000444261 MDM4-007 204542789-204549388 protein_coding
  ENST00000454264 MDM4-203 204516379-204558119 protein_coding
  ENST00000462012 MDM4-008 204537875-204542931 processed_transcript
  ENST00000463049 MDM4-002 204516406-204554201 processed_transcript
  ENST00000470797 MDM4-005 204516383-204532650 processed_transcript
  ENST00000470908 MDM4-003 204516451-204546832 processed_transcript
  ENST00000471783 MDM4-004 204516472-204544599 processed_transcript
  ENST00000507825 MDM4-204 204525519-204546834 protein_coding
  ENST00000612738 MDM4-205 204516379-204558119 protein_coding
  ENST00000614459 MDM4-206 204516379-204558119 protein_coding
  ENST00000616250 MDM4-207 204516379-204558119 protein_coding
  ENST00000621032 MDM4-208 204516406-204554200 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367179ENST00000367182ENST00000367183ENST00000391947ENST00000444261ENST00000454264ENST00000612738ENST00000614459ENST00000621032
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367179 N/A N/A 6.687±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000367182 2.456±0.00 N/A 1.461±0.00 1.047±0.00 N/A 0.899±0.00 N/A 0.247±0.00 N/A 0.770±0.16 2.819±0.00 0.657±0.44 2.041±0.57
ENST00000367183 N/A N/A N/A N/A N/A N/A 1.205±0.00 0.285±0.00 0.951±0.00 N/A 0.900±0.23 0.264±0.00 N/A
ENST00000391947 N/A 1.727±0.00 N/A N/A N/A 0.343±0.00 N/A N/A N/A N/A 1.268±0.00 N/A 1.027±0.00
ENST00000444261 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.187±0.00
ENST00000454264 N/A N/A N/A N/A N/A N/A 0.539±0.00 N/A N/A N/A N/A 0.218±0.00 N/A
ENST00000612738 N/A N/A N/A N/A N/A 1.438±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000614459 N/A 2.825±0.00 N/A N/A 0.420±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000621032 N/A N/A N/A N/A N/A 0.654±0.00 N/A 2.788±0.00 3.771±0.00 N/A 1.340±0.00 0.946±0.00 2.200±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084Z CIL_00084Z_0001 VISTA 1:204154830-204755807

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006461 IDA protein complex assembly
GO:0008270 IEA zinc ion binding
GO:0008283 IEP cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0019899 IPI enzyme binding
GO:0030330 IEP DNA damage response, signal transduction by p53 class mediator
GO:0042177 IMP negative regulation of protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0045023 IEP G0 to G1 transition
GO:0050821 IEP protein stabilization
GO:0071157 IEA negative regulation of cell cycle arrest
GO:0071456 IEP cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057513 mdm4 transformed 3T3 cell double minute 4 homolog (mouse) protein_coding Danio_rerio
ENSMUSG00000054387 Mdm4 transformed mouse 3T3 cell double minute 4 protein_coding Mus_musculus

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