C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cofilin 1, non-muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000056201 Cfl1 10090 + 19:5490485-5494029 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000116560 Cfl1-201 5490485-5494029 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000116560
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000116560 359.996±23.72 342.430±48.06 415.449±9.71 716.463±112.77 397.963±141.19 368.526±47.28 85.236±9.89 251.538±12.04 349.975±221.22 331.767±58.76 29.769±7.59 456.634±27.12 634.105±263.85 137.973±34.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002MN CIL_0002MN_0002 CGP 19:5490485-5510489

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IMP mitotic cytokinesis
GO:0001755 IMP neural crest cell migration
GO:0001842 IMP neural fold formation
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0006468 IDA protein phosphorylation
GO:0006606 IEA protein import into nucleus
GO:0006928 IMP cellular component movement
GO:0007010 ISS cytoskeleton organization
GO:0007015 IMP actin filament organization
GO:0009615 IEA response to virus
GO:0016020 IEA membrane
GO:0022604 ISS regulation of cell morphogenesis
GO:0030010 IMP establishment of cell polarity
GO:0030027 IEA lamellipodium
GO:0030030 ISO cell projection organization
GO:0030042 IEA actin filament depolymerization
GO:0030836 IMP positive regulation of actin filament depolymerization
GO:0030864 IDA cortical actin cytoskeleton
GO:0031252 IEA cell leading edge
GO:0031982 IEA vesicle
GO:0043200 IDA response to amino acid
GO:0045792 ISO negative regulation of cell size
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021124 cfl1 cofilin 1 protein_coding Danio_rerio
ENSG00000172757 CFL1 cofilin 1 (non-muscle) protein_coding Homo_sapiens

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