C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingosine kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107737 Sphk2-001 ENSMUSG00000057342 10090 - 7:45709467-45718002 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000107737
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000107737 17.257±2.73 40.173±2.83 31.378±2.68 25.263±0.00 20.084±6.89 10.445±1.20 14.478±7.17 7.123±1.15 20.104±3.60 11.410±2.32 24.758±8.01 9.323±1.66

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001568 IGI blood vessel development
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005765 IEA lysosomal membrane
GO:0005829 IDA cytosol
GO:0006669 NAS sphinganine-1-phosphate biosynthetic process
GO:0006670 IMP sphingosine metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IGI brain development
GO:0008283 NAS cell proliferation
GO:0008284 IGI positive regulation of cell proliferation
GO:0008481 NAS sphinganine kinase activity
GO:0016020 IDA membrane
GO:0017050 IDA D-erythro-sphingosine kinase activity
GO:0043066 NAS negative regulation of apoptotic process
GO:0046834 IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000222122 DBP-001 protein_coding Homo_sapiens 0 418
ENST00000245222 SPHK2-001 protein_coding Homo_sapiens 0 1487
ENST00000340932 SPHK2-201 protein_coding Homo_sapiens 0 1151
ENST00000426514 SPHK2-007 nonsense_mediated_decay Homo_sapiens 0 1151
ENST00000597434 SPHK2-008 non_stop_decay Homo_sapiens 0 702
ENST00000598088 SPHK2-005 protein_coding Homo_sapiens 0 1487
ENST00000598574 SPHK2-011 retained_intron Homo_sapiens 0 351
ENST00000599029 SPHK2-010 protein_coding Homo_sapiens 0 1471
ENST00000599748 SPHK2-009 protein_coding Homo_sapiens 0 1487
ENST00000600537 SPHK2-004 protein_coding Homo_sapiens 0 1399
ENST00000601704 SPHK2-012 protein_coding Homo_sapiens 0 351
ENST00000601712 SPHK2-003 protein_coding Homo_sapiens 0 704

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