C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057967 Fgf18 10090 - 11:33117430-33147400 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020507 Fgf18-001 33117430-33147400 protein_coding
  ENSMUST00000109363 Fgf18-002 33117430-33146795 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020507ENSMUST00000109363
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020507 1.437±0.14 0.719±0.20 0.307±0.06 0.817±0.23 1.259±0.26 0.481±0.25 1.366±0.58 0.301±0.11 0.095±0.06 3.702±0.99 0.432±0.08 1.767±0.52 0.629±0.62 0.590±0.00
ENSMUST00000109363 N/A N/A N/A N/A 0.660±0.00 0.546±0.08 0.254±0.00 N/A 0.067±0.04 0.696±0.12 0.401±0.00 1.209±0.71 0.694±0.52 0.299±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00092S CIL_00092S_0002 VISTA 11:32891798-33493112
CIL_00097F CIL_00097F_0002 VISTA 11:32999598-33601607
CIL_00088M CIL_00088M_0002 VISTA 11:33042866-33643782
CIL_000977 CIL_000977_0002 VISTA 11:33092412-33693558
CIL_00098H CIL_00098H_0002 VISTA 11:33099828-33701076

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IMP ossification
GO:0001525 IMP angiogenesis
GO:0001957 IMP intramembranous ossification
GO:0001958 IMP endochondral ossification
GO:0002063 IMP chondrocyte development
GO:0005104 TAS fibroblast growth factor receptor binding
GO:0005105 IEA type 1 fibroblast growth factor receptor binding
GO:0005111 IEA type 2 fibroblast growth factor receptor binding
GO:0005576 IEA extracellular region
GO:0005730 IEA nucleolus
GO:0007165 TAS signal transduction
GO:0007399 IEA nervous system development
GO:0008083 IEA growth factor activity
GO:0008284 IMP positive regulation of cell proliferation
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0030324 IMP lung development
GO:0030949 IMP positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032332 IGI positive regulation of chondrocyte differentiation
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043962 fgf18b fibroblast growth factor 18b protein_coding Danio_rerio
ENSDARG00000088048 fgf18a fibroblast growth factor 18a protein_coding Danio_rerio
ENSG00000156427 FGF18 fibroblast growth factor 18 protein_coding Homo_sapiens

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