C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor, alpha 2b
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000071902 Adra2b-201 ENSMUSG00000058620 10090 + 2:127363286-127367221 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071902
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071902 0.250±0.07 0.337±0.19 0.079±0.00 0.210±0.10 0.530±0.06 9.872±4.01 0.474±0.12 0.276±0.04 0.291±0.07 0.265±0.12 4.703±0.00 0.070±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000187 IEA activation of MAPK activity
GO:0001525 IMP angiogenesis
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004935 IMP adrenergic receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007565 IEA female pregnancy
GO:0016021 IEA integral component of membrane
GO:0030168 IEA platelet activation
GO:0032148 IEA activation of protein kinase B activity
GO:0035625 IEA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045777 IEA positive regulation of blood pressure
GO:0051379 IEA epinephrine binding
GO:0070474 IEA positive regulation of uterine smooth muscle contraction
GO:0071883 IEA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000101562 adra2c-001 protein_coding Danio_rerio 0 195
ENST00000620793 ADRA2B-001 protein_coding Homo_sapiens 0 1310

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