C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta sub
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059447 Hadhb 10090 + 5:30155248-30184593 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026841 Hadhb-001 30155248-30184593 protein_coding
  ENSMUST00000114783 Hadhb-003 30155323-30184582 protein_coding
  ENSMUST00000114786 Hadhb-002 30155272-30184587 protein_coding
  ENSMUST00000122934 Hadhb-006 30174958-30179094 retained_intron
  ENSMUST00000123980 Hadhb-005 30155258-30174953 protein_coding
  ENSMUST00000127364 Hadhb-004 30155275-30168273 retained_intron
  ENSMUST00000133414 Hadhb-007 30178561-30180975 processed_transcript
  ENSMUST00000141236 Hadhb-008 30180232-30184236 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026841ENSMUST00000114783ENSMUST00000114786ENSMUST00000123980ENSMUST00000127364ENSMUST00000133414ENSMUST00000141236
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026841 40.570±17.57 13.302±0.83 44.236±9.54 11.080±2.31 43.961±40.68 9.177±1.76 196.639±24.03 35.517±4.91 31.158±22.39 7.186±0.61 104.614±9.45 8.011±3.03 19.925±15.53 17.801±8.55
ENSMUST00000114783 23.173±1.76 N/A N/A N/A 25.190±10.31 12.094±0.00 77.309±4.68 N/A N/A 4.686±1.23 N/A 18.442±13.03 24.655±1.84 N/A
ENSMUST00000114786 38.113±14.98 57.720±7.14 21.025±1.65 2.348±0.35 52.829±14.91 16.664±4.70 226.984±37.33 45.861±5.57 32.209±15.38 17.832±4.95 43.656±7.22 12.015±3.62 9.432±5.14 1.595±0.00
ENSMUST00000123980 N/A N/A N/A 5.046±0.00 N/A N/A N/A N/A N/A N/A N/A 18.910±0.00 10.354±1.84 7.747±0.00
ENSMUST00000127364 N/A N/A N/A 0.166±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000133414 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.917±0.00 N/A
ENSMUST00000141236 111.922±36.54 66.137±9.09 N/A 10.553±0.00 90.997±17.54 49.231±6.25 350.353±0.00 84.949±6.25 42.508±4.41 27.207±7.60 N/A 47.568±6.77 16.479±0.00 12.631±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DK CIL_0007DK_0002 CGP 5:30118301-30184593
CIL_0007DJ CIL_0007DJ_0002 CGP 5:30155248-30205722

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0003857 IEA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0003988 IDA acetyl-CoA C-acyltransferase activity
GO:0004300 IEA enoyl-CoA hydratase activity
GO:0005515 IEA protein binding
GO:0005739 TAS mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005743 IDA mitochondrial inner membrane
GO:0005783 ISS endoplasmic reticulum
GO:0006635 IEA fatty acid beta-oxidation
GO:0016507 IC mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0016508 IEA long-chain-enoyl-CoA hydratase activity
GO:0016509 IMP long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0032403 IEA protein complex binding
GO:0042645 IEA mitochondrial nucleoid
GO:0044822 IEA poly(A) RNA binding
GO:0051287 IEA NAD binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057147 hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta sub protein_coding Danio_rerio
ENSG00000138029 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit protein_coding Homo_sapiens

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