C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deleted in colorectal carcinoma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000060534 Dcc 10090 - 18:71258738-72351069 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073379 Dcc-002 71258990-72351017 protein_coding
  ENSMUST00000114943 Dcc-001 71258738-72351069 protein_coding
  ENSMUST00000126030 Dcc-003 71951906-72351041 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000073379ENSMUST00000114943ENSMUST00000126030
Transcript ID Adipose Adrenal Bladder Brain Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000073379 0.054±0.05 0.038±0.01 0.005±0.00 N/A 0.021±0.00 0.009±0.00 0.007±0.01 0.009±0.00 0.061±0.04 0.004±0.00 0.020±0.01
ENSMUST00000114943 0.090±0.00 0.071±0.02 0.001±0.00 6.794±4.84 N/A N/A 0.019±0.00 N/A 0.068±0.04 N/A N/A
ENSMUST00000126030 N/A 0.028±0.01 0.002±0.00 N/A N/A N/A 0.008±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0001975 IEA response to amphetamine
GO:0003713 IEA transcription coactivator activity
GO:0005042 IEA netrin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006915 IEA apoptotic process
GO:0007411 IEA axon guidance
GO:0010976 IEA positive regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0021965 IMP spinal cord ventral commissure morphogenesis
GO:0030424 IDA axon
GO:0032584 IEA growth cone membrane
GO:0033563 IMP dorsal/ventral axon guidance
GO:0033564 IMP anterior/posterior axon guidance
GO:0038007 IEA netrin-activated signaling pathway
GO:0042802 IEA identical protein binding
GO:0045121 IEA membrane raft
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:1901214 IEA regulation of neuron death
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087980 CABZ01100973.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000090360 DCC (2 of 2) DCC netrin 1 receptor protein_coding Danio_rerio
ENSG00000187323 DCC DCC netrin 1 receptor protein_coding Homo_sapiens

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