C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin G associated kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062234 Gak 10090 - 5:108569411-108629739 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046603 Gak-001 108569414-108629739 protein_coding
  ENSMUST00000133745 Gak-008 108570173-108571869 retained_intron
  ENSMUST00000135225 Gak-002 108569414-108629739 nonsense_mediated_decay
  ENSMUST00000137872 Gak-004 108580079-108625091 retained_intron
  ENSMUST00000139303 Gak-006 108584371-108596828 nonsense_mediated_decay
  ENSMUST00000145467 Gak-003 108569420-108629739 nonsense_mediated_decay
  ENSMUST00000145935 Gak-007 108613632-108629423 processed_transcript
  ENSMUST00000156110 Gak-005 108569411-108591671 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046603ENSMUST00000133745ENSMUST00000135225ENSMUST00000145467ENSMUST00000156110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046603 19.798±3.14 8.550±1.30 14.758±0.00 17.536±4.59 18.249±3.99 41.793±7.33 5.931±1.02 25.191±5.74 13.521±4.21 23.913±2.61 1.861±0.53 23.512±8.06 23.998±8.98 9.760±2.33
ENSMUST00000133745 N/A N/A N/A 42.834±0.00 N/A N/A N/A N/A N/A N/A N/A 42.470±0.00 60.515±1.04 14.179±0.00
ENSMUST00000135225 3.949±1.04 28.135±2.26 N/A N/A 7.596±2.75 15.112±3.56 N/A N/A N/A 3.794±0.00 N/A 5.065±0.19 N/A N/A
ENSMUST00000145467 N/A N/A 3.343±0.00 4.129±0.56 4.386±0.73 7.952±1.65 1.233±0.15 N/A 2.294±0.43 5.086±0.17 0.621±0.20 4.466±0.96 N/A 1.400±0.43
ENSMUST00000156110 N/A N/A 4.582±0.00 N/A 7.162±0.00 N/A N/A 7.164±0.28 5.708±1.06 N/A 1.045±0.22 8.426±1.38 19.355±4.00 2.817±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LS CIL_0006LS_0002 CGP 5:108518554-108629739
CIL_0001Y1 CIL_0001Y1_0002 CGP 5:108569411-108647770

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005794 IEA Golgi apparatus
GO:0006468 IEA protein phosphorylation
GO:0007029 IMP endoplasmic reticulum organization
GO:0007030 IMP Golgi organization
GO:0007049 IEA cell cycle
GO:0009913 IMP epidermal cell differentiation
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0035622 IMP intrahepatic bile duct development
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0048468 IMP cell development
GO:0048853 IMP forebrain morphogenesis
GO:0061436 IMP establishment of skin barrier
GO:0072318 IGI clathrin coat disassembly
GO:0072583 IMP clathrin-mediated endocytosis
GO:2000179 IMP positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039384 gak cyclin G associated kinase protein_coding Danio_rerio
ENSDARG00000090654 GAK (2 of 2) cyclin G associated kinase protein_coding Danio_rerio
ENSG00000178950 GAK cyclin G associated kinase protein_coding Homo_sapiens

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