C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caveolin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062694 Cav3 10090 + 6:112459501-112472871 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075477 Cav3-201 112459501-112472871 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000075477
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000075477 0.279±0.15 0.081±0.03 10.858±0.81 0.134±0.09 6.226±6.75 4.024±0.72 58.227±4.82 0.430±0.18 0.161±0.29 6.046±3.11 44.318±3.88 0.877±0.51 0.158±0.10 0.095±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005S5 CIL_0005S5_0002 CGP 6:112359324-112472871
CIL_0003C9 CIL_0003C9_0002 CGP 6:112459501-112489808

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001778 IMP plasma membrane repair
GO:0002027 IEA regulation of heart rate
GO:0005246 IEA calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005783 ISO endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 ISO plasma membrane
GO:0005901 IDA caveola
GO:0006469 IMP negative regulation of protein kinase activity
GO:0006641 IMP triglyceride metabolic process
GO:0006897 TAS endocytosis
GO:0007009 IMP plasma membrane organization
GO:0007015 IMP actin filament organization
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007520 IMP myoblast fusion
GO:0008016 IEA regulation of heart contraction
GO:0008022 IEA protein C-terminus binding
GO:0008104 IMP protein localization
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010614 IMP negative regulation of cardiac muscle hypertrophy
GO:0010831 IMP positive regulation of myotube differentiation
GO:0014704 IEA intercalated disc
GO:0014819 IEA regulation of skeletal muscle contraction
GO:0014902 IMP myotube differentiation
GO:0016010 IEA dystrophin-associated glycoprotein complex
GO:0016020 IDA membrane
GO:0016049 IEA cell growth
GO:0017015 IMP regulation of transforming growth factor beta receptor signaling pathway
GO:0017080 IEA sodium channel regulator activity
GO:0019870 IEA potassium channel inhibitor activity
GO:0019899 IEA enzyme binding
GO:0030018 IEA Z disc
GO:0030154 IEA cell differentiation
GO:0030315 IDA T-tubule
GO:0031116 IEA positive regulation of microtubule polymerization
GO:0031122 IMP cytoplasmic microtubule organization
GO:0031579 IMP membrane raft organization
GO:0031594 IEA neuromuscular junction
GO:0031982 IEA vesicle
GO:0032403 IEA protein complex binding
GO:0032947 IEA protein complex scaffold
GO:0038009 IEA regulation of signal transduction by receptor internalization
GO:0042383 IDA sarcolemma
GO:0042391 IGI regulation of membrane potential
GO:0042593 IMP glucose homeostasis
GO:0042632 IMP cholesterol homeostasis
GO:0043014 IDA alpha-tubulin binding
GO:0043234 IEA protein complex
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0043409 IMP negative regulation of MAPK cascade
GO:0044325 IPI ion channel binding
GO:0045121 IDA membrane raft
GO:0045792 IEA negative regulation of cell size
GO:0046716 IMP muscle cell cellular homeostasis
GO:0050998 IEA nitric-oxide synthase binding
GO:0051001 IMP negative regulation of nitric-oxide synthase activity
GO:0051394 IEA regulation of nerve growth factor receptor activity
GO:0051647 IMP nucleus localization
GO:0051896 IMP regulation of protein kinase B signaling
GO:0051924 IMP regulation of calcium ion transport
GO:0051926 IMP negative regulation of calcium ion transport
GO:0055013 IMP cardiac muscle cell development
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0060299 IEA negative regulation of sarcomere organization
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060347 IMP heart trabecula formation
GO:0060373 IEA regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060762 IMP regulation of branching involved in mammary gland duct morphogenesis
GO:0061052 IEA negative regulation of cell growth involved in cardiac muscle cell development
GO:0070836 IMP caveola assembly
GO:0071253 IPI connexin binding
GO:0072659 IMP protein localization to plasma membrane
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0090002 IMP establishment of protein localization to plasma membrane
GO:0090279 IEA regulation of calcium ion import
GO:1900744 IMP regulation of p38MAPK cascade
GO:1900825 IEA regulation of membrane depolarization during cardiac muscle cell action potential
GO:1901017 IEA negative regulation of potassium ion transmembrane transporter activity
GO:1901019 IEA regulation of calcium ion transmembrane transporter activity
GO:1901380 IEA negative regulation of potassium ion transmembrane transport
GO:2000649 IEA regulation of sodium ion transmembrane transporter activity
GO:2001288 IEA positive regulation of caveolin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024141 cav3 caveolin 3 protein_coding Danio_rerio
ENSG00000182533 CAV3 caveolin 3 protein_coding Homo_sapiens

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