C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caveolin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182533 CAV3 9606 + 3:8733800-8841808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343849 CAV3-001 8733800-8746765 protein_coding
  ENST00000397368 CAV3-002 8733866-8746756 protein_coding
  ENST00000472766 CAV3-003 8733836-8841808 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000343849ENST00000397368ENST00000472766
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000343849 N/A 2.332±0.00 N/A 5.379±3.42 N/A 0.313±0.16 19.633±2.17 0.040±0.01 N/A 0.626±0.39
ENST00000397368 0.017±0.00 0.265±0.14 0.252±0.00 N/A N/A 0.309±0.00 6.619±0.00 N/A 0.072±0.04 N/A
ENST00000472766 0.038±0.00 0.333±0.00 N/A N/A 0.121±0.00 N/A N/A N/A 0.059±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000001 CIL_000001_0001 CGP 3:8501707-8745040
CIL_0005S5 CIL_0005S5_0001 CGP 3:8619400-8841808
CIL_0003C9 CIL_0003C9_0001 CGP 3:8733800-8841808

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001778 IEA plasma membrane repair
GO:0002027 IMP regulation of heart rate
GO:0005246 IDA calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005901 IEA caveola
GO:0006469 ISS negative regulation of protein kinase activity
GO:0006641 ISS triglyceride metabolic process
GO:0006897 ISS endocytosis
GO:0007009 ISS plasma membrane organization
GO:0007015 IEA actin filament organization
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007517 TAS muscle organ development
GO:0007520 IEA myoblast fusion
GO:0008016 ISS regulation of heart contraction
GO:0008022 IDA protein C-terminus binding
GO:0008104 ISS protein localization
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010614 IMP negative regulation of cardiac muscle hypertrophy
GO:0010831 IEA positive regulation of myotube differentiation
GO:0014704 IEA intercalated disc
GO:0014819 IMP regulation of skeletal muscle contraction
GO:0014902 IEA myotube differentiation
GO:0016010 IDA dystrophin-associated glycoprotein complex
GO:0016020 IEA membrane
GO:0016049 ISS cell growth
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0017080 IDA sodium channel regulator activity
GO:0019870 ISS potassium channel inhibitor activity
GO:0019899 IEA enzyme binding
GO:0030018 ISS Z disc
GO:0030154 ISS cell differentiation
GO:0030315 ISS T-tubule
GO:0031116 ISS positive regulation of microtubule polymerization
GO:0031122 IEA cytoplasmic microtubule organization
GO:0031579 ISS membrane raft organization
GO:0031594 ISS neuromuscular junction
GO:0031982 IEA vesicle
GO:0032403 IDA protein complex binding
GO:0032947 ISS protein complex scaffold
GO:0033292 TAS T-tubule organization
GO:0038009 IMP regulation of signal transduction by receptor internalization
GO:0042383 IDA sarcolemma
GO:0042391 IDA regulation of membrane potential
GO:0042593 ISS glucose homeostasis
GO:0042632 ISS cholesterol homeostasis
GO:0043014 IEA alpha-tubulin binding
GO:0043234 IEA protein complex
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0043409 ISS negative regulation of MAPK cascade
GO:0044325 IPI ion channel binding
GO:0045121 ISS membrane raft
GO:0045792 IMP negative regulation of cell size
GO:0046716 ISS muscle cell cellular homeostasis
GO:0050998 IEA nitric-oxide synthase binding
GO:0051001 ISS negative regulation of nitric-oxide synthase activity
GO:0051394 IMP regulation of nerve growth factor receptor activity
GO:0051647 IEA nucleus localization
GO:0051896 IEA regulation of protein kinase B signaling
GO:0051924 IEA regulation of calcium ion transport
GO:0051926 IDA negative regulation of calcium ion transport
GO:0055013 IEA cardiac muscle cell development
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060299 IMP negative regulation of sarcomere organization
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060347 IEA heart trabecula formation
GO:0060373 IDA regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060762 IEA regulation of branching involved in mammary gland duct morphogenesis
GO:0061052 IEA negative regulation of cell growth involved in cardiac muscle cell development
GO:0070836 IDA caveola assembly
GO:0071253 IDA connexin binding
GO:0072659 ISS protein localization to plasma membrane
GO:0086005 ISS ventricular cardiac muscle cell action potential
GO:0090002 IEA establishment of protein localization to plasma membrane
GO:0090279 IDA regulation of calcium ion import
GO:1900744 IEA regulation of p38MAPK cascade
GO:1900825 IMP regulation of membrane depolarization during cardiac muscle cell action potential
GO:1901017 ISS negative regulation of potassium ion transmembrane transporter activity
GO:1901019 IDA regulation of calcium ion transmembrane transporter activity
GO:1901380 ISS negative regulation of potassium ion transmembrane transport
GO:2000009 NAS negative regulation of protein localization to cell surface
GO:2000060 NAS positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000649 IDA regulation of sodium ion transmembrane transporter activity
GO:2001288 IEA positive regulation of caveolin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024141 cav3 caveolin 3 protein_coding Danio_rerio
ENSMUSG00000062694 Cav3 caveolin 3 protein_coding Mus_musculus

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